Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16855916 | 0.94 | PTGS2 (0.50) | PTGS2PTGS1TUBB1PRKCZCD274 | |
| SCHEMBL16855917 | 0.92 | FGFR2 (0.46) | PTGS2PTGS1TUBB1PRKCZKDM1A | |
| SCHEMBL16855903 | 0.90 | FPR2 (0.42) | PTGS2PTGS1PRKCZCD274GAA | |
| SCHEMBL16856037 | 0.89 | PTGS2 (0.53) | PTGS2PTGS1TUBB1PRKCZCD274 | |
| SCHEMBL16855904 | 0.88 | MGLL (0.44) | PTGS2PTGS1PRKCZCD274CYP17A1 | |
| SCHEMBL16852379 | 0.86 | FAAH (0.41) | PTGS2PTGS1PRKCZKDM1AKDM4E | |
| SCHEMBL16855895 | 0.85 | L3MBTL1 (0.43) | PTGS2PTGS1KDM1AKDM4EGAA | |
| SCHEMBL16852377 | 0.85 | NAAA (0.45) | PTGS2PTGS1PRKCZKDM1AKDM4E | |
| SCHEMBL16855842 | 0.85 | PTGS2 (0.43) | PTGS2PTGS1KDM1ANAAA | |
| SCHEMBL16855899 | 0.85 | L3MBTL1 (0.43) | PTGS2PTGS1KDM1AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951274-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2018-04-24 | — | — | US | disclosed |
| US-20150175884-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-06-25 | — | — | US | disclosed |