Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | STS | P08842 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19865073 | 0.83 | TPSAB1 (0.63) | TPSAB1CYP3A4MEN1KMT2ACA1 | |
| SCHEMBL5696317 | 0.82 | HPGD (0.68) | TPSAB1CYP3A4MEN1KMT2ACA1 | |
| SCHEMBL15678793 | 0.82 | LMNA (0.76) | TPSAB1CYP3A4MEN1KMT2ACA1 | |
| SCHEMBL14623873 | 0.81 | MEN1 (0.83) | TPSAB1CYP3A4MEN1KMT2AEPHX2 | |
| SCHEMBL11434850 | 0.81 | MEN1 (0.83) | TPSAB1CYP3A4MEN1KMT2AEPHX2 | |
| SCHEMBL1951979 | 0.81 | KMT2A (0.61) | TPSAB1CYP3A4MEN1KMT2ACA1 | |
| Hydrochloric Acid SCHEMBL5474583 | 0.81 | HPGD (0.66) | TPSAB1CYP3A4MEN1KMT2ACA1 | |
| SCHEMBL8499126 | 0.80 | MEN1 (0.80) | TPSAB1CYP3A4MEN1KMT2ACA1 | |
| SCHEMBL13716200 | 0.79 | HDAC1 (0.60) | TPSAB1CYP3A4MEN1KMT2ACA1 | |
| SCHEMBL13972900 | 0.79 | HPGD (0.60) | TPSAB1CYP3A4MEN1KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015095301-A2 | CYTOTOXIC PEPTIDES AND CONJUGATES THEREOF | IRM LLC (BM) | 2015-06-25 | — | — | WO | disclosed |