Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.64 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.64 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | NPY1R | P25929 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28820748 | 0.78 | HDAC3 (0.64) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8457651 | 0.78 | HDAC3 (0.64) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL596212 | 0.78 | HDAC3 (0.64) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL596141 | 0.77 | HDAC3 (0.63) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2462288 | 0.74 | HDAC3 (0.59) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL19002178 | 0.74 | HDAC3 (0.58) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| Anetholtrithion SCHEMBL225654 | 0.74 | MEN1 (1.00) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15928850 | 0.74 | HDAC3 (0.58) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL19002183 | 0.74 | HDAC6 (0.58) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL12601934 | 0.72 | HDAC3 (0.56) | HDAC6HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150239864-A1 | 3H-1,2-DITHIOCYCLOPENTENE-3-THIOKETONE COMPOUNDS AND APPLICATION THEREOF | SOOCHOW UNIVERSITY (CN) | 2015-08-27 | — | — | US | claimed |
| EP-2889294-A1 | 3H-1,2-DITHIOCYCLOPENTENE-3-THIOKETONE COMPOUNDS AND APPLICATION THEREOF | Soochow University (CN) | 2015-07-01 | — | — | EP | claimed |
| US-20150239864-A1 | 3H-1,2-DITHIOCYCLOPENTENE-3-THIOKETONE COMPOUNDS AND APPLICATION THEREOF | SOOCHOW UNIVERSITY (CN) | 2015-08-27 | — | — | US | disclosed |
| EP-2889294-A1 | 3H-1,2-DITHIOCYCLOPENTENE-3-THIOKETONE COMPOUNDS AND APPLICATION THEREOF | Soochow University (CN) | 2015-07-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239864-A1 | 3H-1,2-DITHIOCYCLOPENTENE-3-THIOKETONE COMPOUNDS AND APPLICATION THEREOF | TXN2, TXN, TXNRD2 | HDAC6 2840/4885HDAC3 1693/4885HDAC4 3294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.