Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 9/20 | 0.63 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.63 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.63 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.63 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.63 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.63 |
| ▸ | MAOA | P21397 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | PGR | P06401 | 1/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | NPY1R | P25929 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11040858 | 0.81 | HDAC3 (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL9534281 | 0.77 | HDAC3 (0.64) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL16856765 | 0.77 | HDAC6 (0.64) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8457651 | 0.77 | HDAC3 (0.64) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL2428473 | 0.77 | HDAC3 (1.00) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL596212 | 0.77 | HDAC3 (0.64) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL17849753 | 0.77 | HDAC8 (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL16856727 | 0.77 | HDAC3 (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL17849760 | 0.77 | CYP2A6 (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4556769 | 0.76 | HDAC1 (0.61) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4414363-A1 | INDOLYLACETIC DERIVATIVES FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | Miuli Pharma S.r.l. (IT) | 2024-08-14 | — | — | EP | claimed |
| US-20150239864-A1 | 3H-1,2-DITHIOCYCLOPENTENE-3-THIOKETONE COMPOUNDS AND APPLICATION THEREOF | SOOCHOW UNIVERSITY (CN) | 2015-08-27 | — | — | US | claimed |
| EP-2889294-A1 | 3H-1,2-DITHIOCYCLOPENTENE-3-THIOKETONE COMPOUNDS AND APPLICATION THEREOF | Soochow University (CN) | 2015-07-01 | — | — | EP | claimed |
| EP-4414363-A1 | INDOLYLACETIC DERIVATIVES FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | Miuli Pharma S.r.l. (IT) | 2024-08-14 | — | — | EP | disclosed |
| US-20150239864-A1 | 3H-1,2-DITHIOCYCLOPENTENE-3-THIOKETONE COMPOUNDS AND APPLICATION THEREOF | SOOCHOW UNIVERSITY (CN) | 2015-08-27 | — | — | US | disclosed |
| EP-2889294-A1 | 3H-1,2-DITHIOCYCLOPENTENE-3-THIOKETONE COMPOUNDS AND APPLICATION THEREOF | Soochow University (CN) | 2015-07-01 | — | — | EP | disclosed |
| US-8114858-B2 | Derivatives of 4- or 5-aminosalicylic acid | ANTIBE THERAPEUTICS INC. (CA) | 2012-02-14 | — | — | US | disclosed |
| US-8114858-B2 | Derivatives of 4- or 5-aminosalicylic acid | ANTIBE THERAPEUTICS INC. (CA) | 2012-02-14 | — | — | US | disclosed |
| US-8114857-B2 | Derivatives of 4- or 5-aminosalicylic acid | ANTIBE THERAPEUTICS INC. (CA) | 2012-02-14 | — | — | US | disclosed |
| US-8114857-B2 | Derivatives of 4- or 5-aminosalicylic acid | ANTIBE THERAPEUTICS INC. (CA) | 2012-02-14 | — | — | US | disclosed |
| US-8114857-B2 | Derivatives of 4- or 5-aminosalicylic acid | ANTIBE THERAPEUTICS INC. (CA) | 2012-02-14 | — | — | US | disclosed |
| EP-0343573-A1 | Medicines containing 1,2-dithiol-3-thion-S-oxyde compounds | Kali-Chemie Pharma GmbH (DE) | 1989-11-29 | — | — | EP | disclosed |
| EP-0172427-B1 | PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER | Shin-Etsu Chemical Co., Ltd. (JP) | 1989-07-05 | — | — | EP | disclosed |
| US-4758639-A | Process for production of vinyl polymer | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-19 | — | — | US | disclosed |
| US-4757124-A | Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0172427-A2 | Process for production of vinyl chloride polymer | Shin-Etsu Chemical Co., Ltd. (JP) | 1986-02-26 | — | — | EP | disclosed |
| US-4396589-A | Alkali metal complex compounds, and their use in the hydrogenation and nitridation of alkali metals | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1983-08-02 | — | — | US | disclosed |
| US-4370488-A | CATALYSTS FOR HYDROGENATION OF ALFALI METALS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1983-01-25 | — | — | US | disclosed |
| US-4301081-A | FOR USE AS CATALYST FOR HYDROGENATION OF ALKALI METALS TO HYDRIDES OR NITRIDES | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1981-11-17 | — | — | US | disclosed |
| US-4229354-A | COMPLEXING WITH COMPOUNDS OF SULFUR OR OXYGEN | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1980-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239864-A1 | 3H-1,2-DITHIOCYCLOPENTENE-3-THIOKETONE COMPOUNDS AND APPLICATION THEREOF | TXN2, TXN, TXNRD2 | HDAC3 1693/4885HDAC4 3294/4885HDAC1 1647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.