Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL29623841 | 1.00 | LMNA (0.60) | LMNAALDH1A1FFAR3LCKFYN | |
| Glycerin SCHEMBL15061 | 1.00 | LMNA (0.60) | LMNAALDH1A1FFAR3LCKFYN | |
| Glycerin SCHEMBL203757 | 1.00 | LMNA (0.60) | LMNAALDH1A1FFAR3LCKFYN | |
| Glycerin SCHEMBL30460570 | 1.00 | LMNA (0.60) | LMNAALDH1A1FFAR3LCKFYN | |
| Glycerin SCHEMBL33458 | 1.00 | LMNA (0.60) | LMNAALDH1A1FFAR3LCKFYN | |
| Glycerin SCHEMBL1685690 | 1.00 | LMNA (0.60) | LMNAALDH1A1FFAR3LCKFYN | |
| Glycerin SCHEMBL1685695 | 1.00 | LMNA (0.60) | LMNAALDH1A1FFAR3LCKFYN | |
| Glycerin SCHEMBL31032269 | 1.00 | LMNA (0.60) | LMNAALDH1A1FFAR3LCKFYN | |
| Glycerin SCHEMBL8151443 | 1.00 | LMNA (0.60) | LMNAALDH1A1FFAR3LCKFYN | |
| Glycerin SCHEMBL29793596 | 1.00 | LMNA (0.60) | LMNAALDH1A1FFAR3LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992100-A | PLASTICIZED MOLDING MATERIAL | DEUTSCHE GELATINE-FABRIKEN STOESS & CO. GMBH (DE) | 1991-02-12 | — | — | US | claimed |
| US-4914142-A | ADDING UNSATURATED MONOMER TO HIGH MOLECULAR WEIGHT SEED POLYMER, POLYMERIZING IN PRESENCE OF FILM-FORMING AID | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1990-04-03 | — | — | US | claimed |
| US-11261295-B2 | Polyglycerol compositions | CARGILL, INCORPORATED (US) | 2022-03-01 | — | — | US | disclosed |
| US-10865302-B2 | Resin composition and use thereof | ZEON CORPORATION (JP) | 2020-12-15 | — | — | US | disclosed |
| US-20190352460-A1 | POLYGLYCEROL COMPOSITIONS | CARGILL, INCORPORATED (US) | 2019-11-21 | — | — | US | disclosed |
| US-20190040249-A1 | RESIN COMPOSITION AND USE THEREOF | ZEON CORPORATION (JP) | 2019-02-07 | — | — | US | disclosed |
| WO-2018140447-A1 | POLYGLYCEROL COMPOSITIONS | CARGILL, INCORPORATED (US) | 2018-08-02 | — | — | WO | disclosed |
| WO-2018140441-A1 | BINDER COMPRISING REACTION PRODUCTS OF POLYGLYCEROL AND ACID | CARGILL, INCORPORATED (US) | 2018-08-02 | — | — | WO | disclosed |
| US-8529241-B2 | Method for manufacturing thermoplastic resin film, and optical compensation film and polarization plate for liquid crystal display panel | FUJIFILM CORPORATION (JP) | 2013-09-10 | — | — | US | disclosed |
| US-20130221565-A1 | PROCESS FOR PRODUCING THERMOPLASTIC RESIN FILM | FUJIFILM CORPORATION (JP) | 2013-08-29 | — | — | US | disclosed |
| EP-1773572-B1 | METHOD OF MANUFACTURING A THERMOPLASTIC FILM, THERMOPLASTIC FILM AND ITS USE | FUJIFILM CORP (JP) | 2013-06-26 | — | — | EP | disclosed |
| US-20060216437-A1 | Optical compensation film, method for producing optical compensation film, polarization plate and liquid crystal display | KONICA MINOLTA OPTO, INC. (JP) | 2006-09-28 | — | — | US | disclosed |
| US-20060202366-A1 | Optical film, manufacturing method of optical film, optical compensating film, manufacturing method of optical compensating film, polarizing plate, and liquid crystal display | KONICA MINOLTA OPTO, INC. | 2006-09-14 | — | — | US | disclosed |
| US-20060188667-A1 | Optical cellulose acylate film and a method of manufacturing the same | FUJI PHOTO FILM CO., LTD. (JP) | 2006-08-24 | — | — | US | disclosed |
| US-20060078754-A1 | Optical film, polarizing plate and display | KONICA MINOLTA OPTO, INC. (JP) | 2006-04-13 | — | — | US | disclosed |
| WO-2006033459-A1 | CELLULOSE ACYLATE FILM, METHOD OF PRODUCING THE SAME, STRETCHED CELLULOSE ACYLATE FILM AND METHOD OF PRODUCING THE SAME | FUJIFILM CORPORATION (JP) | 2006-03-30 | — | — | WO | disclosed |
| WO-2006006724-A1 | THERMOPLASTIC FILM AND METHOD OF MANUFACTURING THE SAME | FUJIFILM CORPORATION (JP) | 2006-01-19 | — | — | WO | disclosed |
| US-20060004192-A1 | Method of preparing a cellulose acylate, cellulose acylate film, polarizing plate, and liquid crystal display device | FUJI PHOTO FILM CO., LTD. | 2006-01-05 | — | — | US | disclosed |
| JP-2003020390-A | POLYESTER RESIN COMPOSITION AND MATERIAL FOR AGRICULTURE OR WRAPPING | RIKEN VITAMIN CO LTD | 2003-01-24 | — | — | JP | disclosed |
| US-4992100-A | PLASTICIZED MOLDING MATERIAL | DEUTSCHE GELATINE-FABRIKEN STOESS & CO. GMBH (DE) | 1991-02-12 | — | — | US | disclosed |