Glycerin

Glycerin

SCHEMBL33458

CC(=O)O.OCC(O)CO

nearest known ligand 0.60

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Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.60
ALDH1A1 P00352 1/20 0.60
FFAR3 O14843 1/20 0.47
LCK P06239 1/20 0.47
FYN P06241 1/20 0.47
OR51E2 Q9H255 1/20 0.45
SLC22A6 Q4U2R8 1/20 0.40
THRB P10828 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
AKR1B1 P15121 1/20 0.38
TP53 P04637 1/20 0.37
PDE4A P27815 1/20 0.36
SLC22A16 Q86VW1 1/20 0.35
MAPT P10636 1/20 0.35
TGFBR1 P36897 1/20 0.34
ACACB O00763 1/20 0.34
ACACA Q13085 1/20 0.34
KDM4E B2RXH2 1/20 0.34
DUSP3 P51452 1/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerin SCHEMBL29623841 1.00 LMNA (0.60) LMNAALDH1A1FFAR3LCKFYN
Glycerin SCHEMBL15061 1.00 LMNA (0.60) LMNAALDH1A1FFAR3LCKFYN
Glycerin SCHEMBL203757 1.00 LMNA (0.60) LMNAALDH1A1FFAR3LCKFYN
Glycerin SCHEMBL30460570 1.00 LMNA (0.60) LMNAALDH1A1FFAR3LCKFYN
Glycerin SCHEMBL1685690 1.00 LMNA (0.60) LMNAALDH1A1FFAR3LCKFYN
Glycerin SCHEMBL1685695 1.00 LMNA (0.60) LMNAALDH1A1FFAR3LCKFYN
Glycerin SCHEMBL1685689 1.00 LMNA (0.60) LMNAALDH1A1FFAR3LCKFYN
Glycerin SCHEMBL31032269 1.00 LMNA (0.60) LMNAALDH1A1FFAR3LCKFYN
Glycerin SCHEMBL8151443 1.00 LMNA (0.60) LMNAALDH1A1FFAR3LCKFYN
Glycerin SCHEMBL29793596 1.00 LMNA (0.60) LMNAALDH1A1FFAR3LCKFYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8679 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122091401-A Chip solid tantalum capacitor and film coating process thereof 2026-05-26 CN claimed
EP-4742926-A1 AEROSOL-GENERATING SUBSTRATE FOR MITIGATION OF WARM AEROSOL Philip Morris Products S.A. (CH) 2026-05-20 EP claimed
US-12629380-B2 Oral film unit dosage form SWIPP AB (SE) 2026-05-19 US claimed
US-12600840-B2 Cellulose acetate resin composition DAICEL CORPORATION (JP) 2026-04-14 US claimed
EP-3522972-B1 COMBINED OSMOTIC AND HYDROGEL CERVICAL DILATORS AND METHOD OF MAKING SAME MEDICEM TECH S R O (CZ) 2026-01-21 EP claimed
US-12472144-B2 Pharmaceutical composition comprising eliglustat AMNEAL PHARMACEUTICALS LLC (US) 2025-11-18 US claimed
WO-2025229040-A1 SUBSTRATE FOR REDUCING HARSHNESS PERCEPTION PHILIP MORRIS PRODUCTS S.A. (CH) 2025-11-06 WO claimed
US-20250332144-A1 PHARMACEUTICAL COMPOSITION COMPRISING ELIGLUSTAT AMNEAL PHARMACEUTICALS LLC (US) 2025-10-30 US claimed
US-20250325790-A1 COMBINED OSMOTIC AND HYDROGEL CERVICAL DILATORS AND METHOD OF MAKING SAME MEDICEM TECH S R O (CZ) 2025-10-23 US claimed
EP-4631499-A1 DELAYED TIMED RELEASE PHARMACEUTICAL COMPOSITION, PREPARATION METHOD THEREFOR, AND USE THEREOF Shanghai WD Pharmaceutical Co., Ltd (CN) 2025-10-15 EP claimed
US-4370449-A COORDINATION CATALYSTS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1983-01-25 US claimed
US-4296043-A Process for the preparation of benzanthrones BAYER AKTIENGESELLSCHAFT (DE) 1981-10-20 US claimed
EP-0000999-B1 TITANIUM TRICHLORIDE COMPOSITIONS, PREPARATION THEREOF, CATALYST SYSTEM CONTAINING THEM, AND POLYMERISATION OF OLEFINS USING THIS SYSTEM IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-05-27 EP claimed
EP-0005757-B1 PROCESS FOR PREPARING BENZANTHRONES BAYER AG (DE) 1980-10-15 EP claimed
US-4211572-A HYDRAULIC CEMENTS, WATER RETENTIVITY PROMOTER TILE COUNCIL OF AMERICA, INC. (US) 1980-07-08 US claimed
US-4203867-A POLYMERIZATION CATALYST; COMPLEXING WITH TITANIUM TRICHLORIDE AND A LEWIS BASE COMPOUND IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-05-20 US claimed
EP-0000999-A1 Titanium trichloride compositions, preparation thereof, catalyst system containing them, and polymerisation of olefins using this system IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1979-03-07 EP claimed
US-4121646-A Method and apparatus for making molds NATIONAL ENGINEERING COMPANY (US) 1978-10-24 US claimed
US-4102738-A IMPROVING FLAT CRUSH RESISTANCE AMERICAN CYANAMID COMPANY (US) 1978-07-25 US claimed
US-3981798-A LIQUID EXTRACTION USING CERTAIN ETHERS AND ESTERSMONO-ETHYL OR MONO-METHYL ETHER OF GLYCERINE, GLYCERINE MONO- OR DI-ACETATE NALCO CHEMICAL COMPANY (US) 1976-09-21 US claimed