Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 7/20 | 0.52 |
| ▸ | EGLN1 | Q9GZT9 | 9/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16857863 | 0.90 | EGLN1 (0.42) | MGLLEGLN1 | |
| SCHEMBL16857747 | 0.89 | MGLL (0.45) | MGLLEGLN1 | |
| SCHEMBL16857775 | 0.89 | EGLN1 (0.49) | MGLLEGLN1 | |
| SCHEMBL3036128 | 0.88 | EGLN1 (0.62) | MGLLEGLN1 | |
| SCHEMBL16857701 | 0.88 | MGLL (0.45) | MGLLEGLN1 | |
| SCHEMBL16857729 | 0.88 | EGLN1 (0.44) | MGLLEGLN1PPARG | |
| SCHEMBL16857799 | 0.86 | EGLN1 (0.48) | MGLLEGLN1PPARG | |
| SCHEMBL16857765 | 0.86 | EGLN1 (0.48) | MGLLEGLN1 | |
| SCHEMBL16857828 | 0.86 | EGLN1 (0.50) | MGLLEGLN1 | |
| SCHEMBL16857754 | 0.86 | EGLN1 (0.44) | MGLLEGLN1CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396316-B1 | QUINAZOLINONES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-07-01 | — | — | EP | claimed |