Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 13/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.37 |
| ▸ | SELE | P16581 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16857701 | 0.91 | MGLL (0.45) | MGLLEGLN1ICAM1SELE | |
| SCHEMBL16857895 | 0.90 | EGLN1 (0.41) | MGLLEGLN1 | |
| SCHEMBL3031507 | 0.89 | EGLN1 (0.56) | MGLLEGLN1 | |
| SCHEMBL16857736 | 0.89 | MGLL (0.52) | MGLLEGLN1 | |
| SCHEMBL16857885 | 0.86 | EGLN1 (0.42) | EGLN1 | |
| SCHEMBL16857906 | 0.84 | EGLN1 (0.53) | EGLN1 | |
| SCHEMBL16857921 | 0.84 | EGLN1 (0.41) | EGLN1 | |
| SCHEMBL16857746 | 0.84 | EGLN1 (0.43) | EGLN1 | |
| SCHEMBL16857739 | 0.84 | EGLN1 (0.43) | EGLN1 | |
| SCHEMBL16857770 | 0.83 | EGLN1 (0.41) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396316-B1 | QUINAZOLINONES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-07-01 | — | — | EP | claimed |