Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 5/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 13/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3025282 | 0.86 | EGLN1 (0.55) | EGLN1 | |
| SCHEMBL16857813 | 0.85 | EGLN1 (0.49) | EGLN1 | |
| SCHEMBL16857823 | 0.84 | EGLN1 (0.47) | SPREGLN1MGLL | |
| SCHEMBL16857764 | 0.82 | EGLN1 (0.50) | EGLN1MGLL | |
| SCHEMBL3038928 | 0.81 | EGLN1 (0.43) | SPREGLN1 | |
| SCHEMBL16857774 | 0.80 | SPR (0.52) | SPREGLN1 | |
| SCHEMBL16857824 | 0.79 | EGLN1 (0.44) | SPREGLN1MGLL | |
| SCHEMBL16857814 | 0.79 | SPR (0.42) | SPREGLN1MGLL | |
| SCHEMBL16857841 | 0.79 | EGLN1 (0.41) | SPREGLN1MGLL | |
| SCHEMBL16857766 | 0.78 | EGLN1 (0.52) | EGLN1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396316-B1 | QUINAZOLINONES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-07-01 | — | — | EP | claimed |