SCHEMBL1685901

SCHEMBL1685901

CC(C)=CCCC(C)=CCS(=O)(=O)CC=C(C)CCC=C(C)C

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.60
ALOX15 P16050 3/20 0.56
MEN1 O00255 3/20 0.56
CYP3A4 P08684 2/20 0.56
MAPT P10636 3/20 0.54
ALDH1A1 P00352 3/20 0.54
UGT1A1 P22309 1/20 0.54
FNTA P49354 2/20 0.53
FNTB P49356 2/20 0.53
SQLE Q14534 2/20 0.52
KDM4E B2RXH2 2/20 0.50
ATM Q13315 1/20 0.50
TRPA1 O75762 1/20 0.49
POLB P06746 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1685900 1.00 KMT2A (0.60) KMT2AALOX15MEN1CYP3A4MAPT
SCHEMBL16654337 1.00 KMT2A (0.60) KMT2AALOX15MEN1CYP3A4MAPT
SCHEMBL10986149 0.98 KMT2A (0.64) KMT2AALOX15MEN1CYP3A4MAPT
SCHEMBL9017121 0.98 KMT2A (0.64) KMT2AALOX15MEN1CYP3A4MAPT
SCHEMBL794674 0.85 KMT2A (0.58) KMT2AALOX15MEN1CYP3A4MAPT
SCHEMBL794675 0.85 KMT2A (0.58) KMT2AALOX15MEN1CYP3A4MAPT
SCHEMBL11787183 0.85 KMT2A (0.44) KMT2AALOX15MEN1CYP3A4MAPT
SCHEMBL11787182 0.85 KMT2A (0.44) KMT2AALOX15MEN1CYP3A4MAPT
SCHEMBL6927178 0.82 KMT2A (0.46) KMT2AALOX15MEN1CYP3A4MAPT
SCHEMBL6927170 0.82 KMT2A (0.46) KMT2AALOX15MEN1CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1218918-C Synthesis of geranyl geraniol UNIV ZHEJIANG (CN) 2005-09-14 CN claimed
CN-1490292-A Synthesis of geranyl geraniol 浙江大学 2004-04-21 CN claimed
JP-1233278-A None JP disclosed
JP-63250364-A None JP disclosed
CN-114874072-B Preparation method of geranylgeraniol 广西民族师范学院 2023-06-23 CN disclosed
CN-114874072-A Preparation method of geranylgeraniol 广西民族师范学院 2022-08-09 CN disclosed
US-20220025419-A1 N-GLYCOSYLATION OF PEPTIDES AND PROTEINS GLYCOVAXYN AG (CH) 2022-01-27 US disclosed
EP-3774707-A1 PROCESS OF VITAMIN K 2 DERIVATIVES PREPARATION INSTYTUT FARMACEUTYCZNY (PL) 2021-02-17 EP disclosed
US-10800735-B2 Intermediate compound for manufacturing bixin ethyl ester and method of manufacturing the same MYONGJI UNIVERSITY INDUSTRY AND ACADEMIA COOPERATION FOUNDATION (KR) 2020-10-13 US disclosed
CN-111592477-A Novel intermediate compound for preparing norbixin or bixin ethyl ester and preparation method thereof 明知大学校产学协力团 2020-08-28 CN disclosed
US-20200262786-A1 NOVEL INTERMEDIATE COMPOUND FOR MANUFACTURING BIXIN ETHYL ESTER AND METHOD OF MANUFACTURING THE SAME MYONGI UNIVERSITY INDUSTRY AND ACADEMIA COOPERATION FOUNDATION (KR) 2020-08-20 US disclosed
US-5073659-A Alkylation, Grignard reagent, zinc chloride catalyst and coppe r compound EISAI CO., LTD. (JP) 1991-12-17 US disclosed
CN-1049650-A The terpenic preparation method EISAI CO LTD (JP) 1991-03-06 CN disclosed
EP-0414106-A2 Process for the preparation of terpenes Eisai Co., Ltd. (JP) 1991-02-27 EP disclosed
JP-H01233278-A PRODUCTION OF OPTICALLY ACTIVE ALPHA-TOCOTRIENOL EISAI CO LTD 1989-09-19 JP disclosed
JP-S63250364-A PRODUCTION OF GERANYLPHENYL SULFONE KURARAY CO LTD 1988-10-18 JP disclosed
EP-0243849-A2 Process for the production of polyprenoid type compounds YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED (IL) 1987-11-04 EP disclosed
EP-0027421-B1 PROCESS FOR THE PREPARATION OF UNSATURATED SULPHONES, AND SULPHONES OBTAINED ANVAR Agence Nationale de Valorisation de la Recherche (FR) 1982-12-29 EP disclosed
US-4343952-A SULFONATION OF DIENE WITH SULFINATE, PALLADIUM CATALYST AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) 1982-08-10 US disclosed
EP-0027421-A1 Process for the preparation of unsaturated sulphones, and sulphones obtained ANVAR Agence Nationale de Valorisation de la Recherche (FR) 1981-04-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220025419-A1 N-GLYCOSYLATION OF PEPTIDES AND PROTEINS PGLS, NGLY1, PTMS KMT2A 4219/4885ALOX15 4207/4885MEN1 1349/4885
US-20200262786-A1 NOVEL INTERMEDIATE COMPOUND FOR MANUFACTURING BIXIN ETHYL ESTER AND METHOD OF MANUFACTURING THE SAME BRIX1, CYP4X1, BROX KMT2A 3436/4885ALOX15 199/4885MEN1 3013/4885
US-10800735-B2 Intermediate compound for manufacturing bixin ethyl ester and method of manufacturing the same BRIX1, BROX, CYP4X1 KMT2A 3255/4885ALOX15 190/4885MEN1 2744/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.