Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17892024 | 0.89 | ABCB1 (0.66) | ABCB1L3MBTL1RXRAMTNR1AMTNR1B | |
| SCHEMBL22193705 | 0.81 | ABCB1 (0.70) | ABCB1L3MBTL1RXRANPC1RAB9A | |
| SCHEMBL8965051 | 0.81 | ABCB1 (0.62) | ABCB1L3MBTL1MTNR1AMTNR1BNPC1 | |
| SCHEMBL7971405 | 0.79 | TAAR1 (0.55) | L3MBTL1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL30040153 | 0.79 | TAAR1 (0.55) | L3MBTL1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL16815580 | 0.79 | ABCB1 (0.60) | ABCB1L3MBTL1RXRAMTNR1AMTNR1B | |
| SCHEMBL24041799 | 0.77 | ABCB1 (0.74) | ABCB1NPC1RAB9AHTR1ADRD2 | |
| SCHEMBL1388037 | 0.77 | RXRA (0.60) | ABCB1RXRANPC1RAB9APOLB | |
| SCHEMBL16018989 | 0.77 | ABCB1 (0.68) | ABCB1RXRANPC1RAB9AHTR1A | |
| SCHEMBL8677245 | 0.77 | ABCB1 (0.64) | ABCB1RXRAMTNR1AMTNR1BNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015097123-A1 | NEW THIENOPYRIMIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2015-07-02 | — | — | WO | disclosed |