Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | CFD | P00746 | 2/20 | 0.54 |
| ▸ | F11 | P03951 | 2/20 | 0.54 |
| ▸ | TPSB2 | P20231 | 2/20 | 0.54 |
| ▸ | PLG | P00747 | 1/20 | 0.54 |
| ▸ | PLAU | P00749 | 1/20 | 0.54 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.54 |
| ▸ | F7 | P08709 | 1/20 | 0.54 |
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 2/20 | 0.52 |
| ▸ | MMP12 | P39900 | 2/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16861302 | 0.89 | ABCB1 (0.63) | ABCB1L3MBTL1RXRAFFAR1NPC1 | |
| SCHEMBL31757965 | 0.86 | CFD (0.68) | L3MBTL1CFDF11TPSB2PLG | |
| SCHEMBL1007508 | 0.86 | CFD (0.68) | L3MBTL1CFDF11TPSB2PLG | |
| SCHEMBL5122876 | 0.84 | MTNR1A (0.57) | ABCB1L3MBTL1CFDF11TPSB2 | |
| SCHEMBL21438534 | 0.84 | HSD17B10 (0.68) | ABCB1L3MBTL1HTR1ADRD2PTGER1 | |
| SCHEMBL5092502 | 0.84 | CFD (0.58) | L3MBTL1CFDF11TPSB2PLG | |
| SCHEMBL22193705 | 0.83 | ABCB1 (0.70) | ABCB1L3MBTL1RXRANPC1RAB9A | |
| SCHEMBL8965051 | 0.83 | ABCB1 (0.62) | ABCB1L3MBTL1NPC1RAB9AATM | |
| SCHEMBL28900188 | 0.82 | PTGER1 (0.68) | CFDF11TPSB2PLGPLAU | |
| SCHEMBL2539350 | 0.82 | L3MBTL1 (0.53) | L3MBTL1CFDF11TPSB2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3240419-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | Dow Agrosciences LLC (US) | 2017-11-08 | — | — | EP | disclosed |
| EP-3240420-A1 | USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | Dow Agrosciences LLC (US) | 2017-11-08 | — | — | EP | disclosed |
| WO-2016109303-A1 | USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109302-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |