SCHEMBL16865155

SCHEMBL16865155

COC(=O)C1(C(=O)OCc2ccc(COC(=O)C3(C(=O)OC)CC3C)cc2)CC1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 2/20 0.46
CYP19A1 P11511 2/20 0.46
MAPT P10636 1/20 0.42
CYP3A4 P08684 2/20 0.41
ADAM17 P78536 5/20 0.38
TSHR P16473 3/20 0.38
ABL1 P00519 1/20 0.38
RIN1 Q13671 1/20 0.38
ALDH1A1 P00352 4/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
NPC1 O15118 2/20 0.37
KDM4E B2RXH2 1/20 0.37
GAA P10253 1/20 0.37
HPGD P15428 1/20 0.37
MAPK1 P28482 1/20 0.37
HSD17B10 Q99714 1/20 0.37
KMT2A Q03164 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
RAB9A P51151 1/20 0.36
CASP1 P29466 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16865156 0.89 CYP17A1 (0.39) CYP17A1CYP19A1MAPTCYP3A4ADAM17
SCHEMBL32674103 0.85 ALDH1A1 (0.53) CYP17A1CYP19A1TSHRALDH1A1SMN1; SMN2
SCHEMBL16865202 0.81 ALDH1A1 (0.49) CYP17A1CYP19A1TSHRALDH1A1SMN1; SMN2
SCHEMBL16865152 0.79 ADAM17 (0.35) CYP17A1CYP19A1MAPTCYP3A4ADAM17
SCHEMBL25317306 0.79 ALDH1A1 (0.50) CYP17A1CYP19A1TSHRALDH1A1MAPK1
SCHEMBL32674206 0.79 ALDH1A1 (0.50) CYP17A1CYP19A1TSHRALDH1A1MAPK1
SCHEMBL16865201 0.79 MAPT (0.35) MAPTTSHRALDH1A1KMT2ANPSR1
SCHEMBL9017773 0.78 NPSR1 (0.37) MAPTTSHRALDH1A1KMT2ANPSR1
SCHEMBL16865212 0.76 CYP17A1 (0.37) CYP17A1CYP19A1MAPTCYP3A4ADAM17
SCHEMBL16865196 0.75 ALDH1A1 (0.43) CYP17A1CYP19A1CYP3A4TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150188193-A1 NON-AQUEOUS LIQUID ELECTROLYTE FOR SECONDARY BATTERY AND SECONDARY BATTERY FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed