SCHEMBL16865156

SCHEMBL16865156

C=Cc1ccc(COC(=O)C2(C(=O)OC)CC2C)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 1/20 0.39
CYP19A1 P11511 1/20 0.39
CYP3A4 P08684 2/20 0.36
MAPT P10636 1/20 0.36
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
MIF P14174 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
HIF1A Q16665 1/20 0.34
ADAM17 P78536 5/20 0.33
TP53 P04637 1/20 0.33
TUBB4A P04350 1/20 0.33
TUBB P07437 1/20 0.33
TUBA3C P0DPH7 1/20 0.33
TUBA1B P68363 1/20 0.33
TUBA4A P68366 1/20 0.33
TUBB4B P68371 1/20 0.33
TUBB3 Q13509 1/20 0.33
TUBB2A Q13885 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16865155 0.89 CYP17A1 (0.46) CYP17A1CYP19A1CYP3A4MAPTKMT2A
SCHEMBL16865212 0.88 CYP17A1 (0.37) CYP17A1CYP19A1CYP3A4MAPTTAS1R3
SCHEMBL16865184 0.79 MEN1 (0.36) CYP17A1CYP19A1MAPTTAS1R3TAS1R1
SCHEMBL32674103 0.76 ALDH1A1 (0.53) CYP17A1CYP19A1KMT2ATSHRCYP2C19
SCHEMBL16865152 0.73 ADAM17 (0.35) CYP17A1CYP19A1CYP3A4MAPTMEN1
SCHEMBL16865202 0.72 ALDH1A1 (0.49) CYP17A1CYP19A1KMT2ATSHRCYP2C19
SCHEMBL16865166 0.71 NPC1 (0.38) MAPTMEN1KMT2ATSHRSLC6A2
SCHEMBL12231040 0.71 ALDH1A1 (0.43) MAPTTAS1R3TAS1R1MIFMEN1
SCHEMBL1051823 0.71 ALDH1A1 (0.58) CYP3A4MAPTTAS1R3TAS1R1MIF
SCHEMBL25317306 0.71 ALDH1A1 (0.50) CYP17A1CYP19A1KMT2ATSHRSLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150188193-A1 NON-AQUEOUS LIQUID ELECTROLYTE FOR SECONDARY BATTERY AND SECONDARY BATTERY FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed