Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31498989 | 1.00 | TSHR (0.60) | TSHRCXCL8LMNAADRA2AADRA2B | |
| SCHEMBL4061649 | 0.85 | KMT2A (0.56) | TSHRCXCL8LMNAADRA2AADRA2B | |
| SCHEMBL15129488 | 0.85 | TSHR (0.48) | TSHRCXCL8ADRA2AADRA2BADRA2C | |
| SCHEMBL30902223 | 0.84 | TDP1 (0.61) | TSHRCXCL8LMNAADRA2AADRA2B | |
| SCHEMBL3279472 | 0.84 | TDP1 (0.61) | TSHRCXCL8LMNAADRA2AADRA2B | |
| SCHEMBL31482338 | 0.81 | LMNA (0.53) | TSHRLMNAADRA2AADRA2BADRA2C | |
| SCHEMBL8663534 | 0.81 | LMNA (0.53) | TSHRLMNAADRA2AADRA2BADRA2C | |
| SCHEMBL2558800 | 0.80 | MEN1 (0.46) | TSHRCXCL8LMNAADRA2AADRA2B | |
| SCHEMBL17066099 | 0.80 | ALDH1A1 (0.59) | TSHRCXCL8LMNAADRA2AADRA2B | |
| SCHEMBL11175497 | 0.80 | GAA (0.49) | TSHRCXCL8LMNAADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1141085-B1 | PROCESS FOR PARTIAL OXIDATION OF POLYOXYALKYLENE POLYOL COMPOSITIONS TO POLYCARBOXYLIC ACID COMPOSITIONS | RESOLUTION RES NEDERLAND BV (NL) | 2005-07-27 | — | — | EP | claimed |
| US-12577373-B2 | Carbodiimide composition, curing agent composition, coating composition and resin cured product | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2026-03-17 | — | — | US | disclosed |
| US-20230135772-A1 | CARBODIIMIDE COMPOSITION, CURING AGENT COMPOSITION, COATING COMPOSITION AND RESIN CURED PRODUCT | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2023-05-04 | — | — | US | disclosed |
| US-20230057142-A1 | LIGHT EMITTING DEVICE AND POLYCYCLIC COMPOUND FOR THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2023-02-23 | — | — | US | disclosed |
| EP-4130154-A1 | CARBODIIMIDE COMPOSITION, HARDENER COMPOSITION, COATING COMPOSITION, AND CURED RESIN OBJECT | Asahi Kasei Kabushiki Kaisha (JP) | 2023-02-08 | — | — | EP | disclosed |
| CN-112940023-A | Organic compound, application thereof and organic electroluminescent device adopting organic compound | 北京鼎材科技有限公司 | 2021-06-11 | — | — | CN | disclosed |
| WO-2020203603-A1 | REVERSIBLE THERMOCHROMIC COMPOSITION, REVERSIBLE THERMOCHROMIC MICROCAPSULE PIGMENT COMPRISING SAME, AND WRITING INSTRUMENT USING SAME | パイロットインキ株式会社 | 2020-10-08 | — | — | WO | disclosed |
| US-9695260-B2 | Method for producing olefin block polymer using plurality of types of transition metal catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-07-04 | — | — | US | disclosed |
| US-9593194-B2 | Method for producing olefin block polymer using group 4 transition metal complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-03-14 | — | — | US | disclosed |
| US-9200093-B2 | Polymerization method using surfactant-containing particle | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-12-01 | — | — | US | disclosed |
| US-4524104-A | ACRYLIC COPOLYMER AND BLOCKED ISOCYANATE | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 1985-06-18 | — | — | US | disclosed |
| US-4511624-A | TERMOPLASTIC STRAIGH CHAIN POLYURETHANE | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 1985-04-16 | — | — | US | disclosed |
| US-4446300-A | DIELECTRICS, FORMING TRIS/2-HYDROXYETHYL/ISOCYANURATE IN SITU FROM CYANURIC ACID AND ETHYLENE CARBONATE | THE P. D. GEORGE COMPANY (US) | 1984-05-01 | — | — | US | disclosed |
| US-4430489-A | HIGHLY REACTIVE CURING AGENT | THIOKOL CORPORATION (US) | 1984-02-07 | — | — | US | disclosed |
| EP-0093491-A1 | One-package, heat-curable compositions suitable for use as sealants, solid coatings and moldings | MORTON THIOKOL, INC. (US) | 1983-11-09 | — | — | EP | disclosed |
| US-4144260-A | Production of aluminum salts of N-nitroso-N-alkyl-hydroxylamines | BASF AKTIENGESELLSCHAFT (DE) | 1979-03-13 | — | — | US | disclosed |
| US-4124400-A | Flame retardant polymer compositions | MONSANTO COMPANY (US) | 1978-11-07 | — | — | US | disclosed |
| US-4113706-A | Aromatic imino acids and resins derived therefrom | THE P. D. GEORGE COMPANY (US) | 1978-09-12 | — | — | US | disclosed |
| US-4082749-A | FROM CARBOXAMIDES AND ALKALI METAL HYPOCHLORITE, CATALYST | BASF AKTIENGESELLSCHAFT (DT) | 1978-04-04 | — | — | US | disclosed |
| US-4069209-A | DIELECTRIC COATINGS FOR WIRES | THE P. D. GEORGE COMPANY (US) | 1978-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12577373-B2 | Carbodiimide composition, curing agent composition, coating composition and resin cured product | CD38, PARP9, MCCC2 | TSHR 4705/4885CXCL8 4800/4885LMNA 1936/4885 |
| US-20230057142-A1 | LIGHT EMITTING DEVICE AND POLYCYCLIC COMPOUND FOR THE SAME | LAGE3, ALG3, ELP1 | TSHR 4306/4885CXCL8 469/4885LMNA 1020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.