Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 5/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16867602 | 0.93 | NAAA (0.37) | NAAAGAACTSDCHRM2CHRM1 | |
| SCHEMBL16864944 | 0.88 | GAA (0.37) | GAACTSDBACE1 | |
| SCHEMBL16865263 | 0.85 | NAAA (0.37) | NAAAGAACTSDCHRM2CHRM1 | |
| SCHEMBL16865260 | 0.82 | GAA (0.38) | NAAAGAACTSDCHRM2CHRM1 | |
| SCHEMBL16859437 | 0.82 | NAAA (0.35) | NAAAGAACTSDBACE1 | |
| SCHEMBL16859435 | 0.82 | NAAA (0.35) | NAAAGAACTSDBACE1 | |
| SCHEMBL16859436 | 0.82 | NAAA (0.35) | NAAAGAACTSDBACE1 | |
| SCHEMBL16865267 | 0.82 | KMT2A (0.41) | NAAA | |
| SCHEMBL16865256 | 0.81 | GAA (0.34) | NAAAGAACTSD | |
| SCHEMBL16865246 | 0.81 | KMT2A (0.38) | NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9549555-B2 | Macrocyclic picolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2017-01-24 | — | — | US | disclosed |
| US-9549555-B2 | Macrocyclic picolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2017-01-24 | — | — | US | disclosed |
| US-9247741-B2 | Use of macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2016-02-02 | — | — | US | disclosed |
| US-9247741-B2 | Use of macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2016-02-02 | — | — | US | disclosed |
| US-20150183759-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC | 2015-07-02 | — | — | US | disclosed |
| US-20150181867-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2015-07-02 | — | — | US | disclosed |
| US-20150181867-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2015-07-02 | — | — | US | disclosed |
| WO-2015100182-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2015-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150183759-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CYP51A1, PFAS, AADAC | NAAA 587/4885GAA 1379/4885CTSD 1416/4885 |
| US-20150181867-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | FKBP14, CYP4F12, CYP1A2 | NAAA 1708/4885GAA 2561/4885CTSD 2050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.