SCHEMBL16865409

SCHEMBL16865409

O=C1N(c2ccccc2)C(=O)C(NCc2ccccc2)(c2ccccc2)C(=O)N1C1CCCCC1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.43
ALDH1A1 P00352 1/20 0.38
POLB P06746 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
BACE1 P56817 1/20 0.37
BACE2 Q9Y5Z0 1/20 0.37
LMNA P02545 1/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
EPHX1 P07099 1/20 0.36
HPGD P15428 1/20 0.36
CHRM3 P20309 1/20 0.36
ELANE P08246 1/20 0.36
HRH3 Q9Y5N1 1/20 0.36
HSD11B1 P28845 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16865445 0.71 ELANE (0.41) L3MBTL1ALDH1A1POLBMEN1KMT2A
SCHEMBL16865431 0.69 CYP2C19 (0.41) L3MBTL1ALDH1A1POLBMEN1KMT2A
SCHEMBL11610967 0.69 NPSR1 (0.46) ALDH1A1POLBMEN1KMT2ALMNA
SCHEMBL15131572 0.69 CES2 (0.49) L3MBTL1ALDH1A1LMNASMN1; SMN2HSD11B1
SCHEMBL16865404 0.68 MEN1 (0.47) L3MBTL1MEN1KMT2AELANE
SCHEMBL16865446 0.67 NPSR1 (0.51) ELANE
SCHEMBL11649915 0.67 HPGD (0.46) L3MBTL1ALDH1A1MEN1KMT2AHTT
SCHEMBL16865395 0.67 NPSR1 (0.44) ALDH1A1BACE1
SCHEMBL17716280 0.67 NPSR1 (0.44) ALDH1A1BACE1BACE2
SCHEMBL16865385 0.66 ALDH1A1 (0.48) L3MBTL1ALDH1A1MEN1KMT2ACHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND C1R, C1S, C3AR1 L3MBTL1 700/4885ALDH1A1 2148/4885POLB 2849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.