SCHEMBL16865404

SCHEMBL16865404

O=C1N(c2ccccc2)C(=O)C(Cc2ccccc2)(Sc2ccc(Cl)cc2)C(=O)N1C1CCCCC1

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.47
KMT2A Q03164 7/20 0.47
L3MBTL1 Q9Y468 1/20 0.43
SMO Q99835 2/20 0.39
ELANE P08246 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16865396 0.76 ELANE (0.53) MEN1KMT2AELANE
SCHEMBL16865416 0.70 ELANE (0.46) MEN1KMT2AELANE
SCHEMBL16865385 0.69 ALDH1A1 (0.48) MEN1KMT2AL3MBTL1
SCHEMBL16865409 0.68 L3MBTL1 (0.43) MEN1KMT2AL3MBTL1ELANE
SCHEMBL16865444 0.68 EP300 (0.42) MEN1KMT2AELANE
SCHEMBL17716279 0.67 ELANE (0.51) MEN1KMT2AL3MBTL1ELANE
SCHEMBL11610967 0.65 NPSR1 (0.46) MEN1KMT2A
SCHEMBL15131572 0.64 CES2 (0.49) L3MBTL1
SCHEMBL11649915 0.62 HPGD (0.46) MEN1KMT2AL3MBTL1
SCHEMBL21334211 0.61 NPSR1 (0.43) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND C1R, C1S, C3AR1 MEN1 3294/4885KMT2A 1571/4885L3MBTL1 700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.