Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17794053 | 0.84 | LMNA (0.68) | MAPTSMN1; SMN2LMNAALDH1A1MAPK1 | |
| SCHEMBL9841223 | 0.75 | BACE1 (0.46) | MAPTSMN1; SMN2GAALMNAALDH1A1 | |
| SCHEMBL16865397 | 0.72 | BACE1 (0.43) | MAPTSMN1; SMN2LMNAALDH1A1MAPK1 | |
| SCHEMBL11925118 | 0.71 | LMNA (0.56) | SMN1; SMN2LMNATSHRCYP2C19REN | |
| SCHEMBL11426802 | 0.70 | LMNA (0.64) | MAPTSMN1; SMN2GAARAB9ALMNA | |
| SCHEMBL11696953 | 0.69 | MAPT (1.00) | MAPTSMN1; SMN2GAARAB9AALDH1A1 | |
| SCHEMBL16867619 | 0.69 | BACE1 (0.41) | MAPTSMN1; SMN2LMNAALDH1A1MAPK1 | |
| (R)-Methylphenobarbital SCHEMBL11789851 | 0.69 | LMNA (1.00) | LMNATSHRCYP2C19KMT2AMEN1 | |
| Mephobarbital SCHEMBL35624 | 0.69 | LMNA (1.00) | LMNATSHRCYP2C19KMT2AMEN1 | |
| (S)-Methylphenobarbital SCHEMBL35625 | 0.69 | LMNA (1.00) | LMNATSHRCYP2C19KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150185368-A1 | OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND | FUJIFILM CORPORATION (JP) | 2015-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150185368-A1 | OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND | C1R, C1S, C3AR1 | MAPT 1367/4885SMN1; SMN2 4738/4885GAA 4562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.