SCHEMBL16865420

SCHEMBL16865420

CCS(=O)(=O)C1(Cc2ccccc2)C(=O)N(C)C(=O)N(c2ccccc2)C1=O

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ELANE P08246 7/20 0.54
NPSR1 Q6W5P4 1/20 0.38
BACE1 P56817 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
THPO P40225 1/20 0.35
NISCH Q9Y2I1 1/20 0.35
MAPK1 P28482 1/20 0.34
HTR7 P34969 1/20 0.34
ITGB2 P05107 2/20 0.33
ICAM1 P05362 2/20 0.33
ITGAL P20701 2/20 0.33
OPRM1 P35372 1/20 0.33
OPRL1 P41146 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16867647 0.75 ELANE (0.51) ELANENPSR1ALDH1A1CYP1A2CYP3A4
SCHEMBL16865451 0.72 ELANE (0.51) ELANENPSR1ALDH1A1CYP1A2CYP3A4
SCHEMBL16867611 0.72 ELANE (0.51) ELANENPSR1BACE1ALDH1A1CYP1A2
SCHEMBL13879387 0.72 ELANE (0.59) ELANENPSR1BACE1ALDH1A1CYP1A2
SCHEMBL4428745 0.70 ELANE (0.74) ELANENPSR1ALDH1A1CYP1A2CYP3A4
SCHEMBL17716270 0.69 ELANE (0.87) ELANENPSR1ALDH1A1CYP1A2CYP3A4
SCHEMBL16865402 0.69 ELANE (0.48) ELANEALDH1A1
SCHEMBL16865406 0.69 ELANE (0.50) ELANENPSR1ALDH1A1CYP1A2CYP3A4
SCHEMBL10645739 0.68 ELANE (0.56) ELANENPSR1BACE1ALDH1A1CYP2C19
SCHEMBL16867610 0.68 ELANE (0.46) ELANENPSR1ALDH1A1NISCHMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND C1R, C1S, C3AR1 ELANE 2715/4885NPSR1 2710/4885BACE1 1296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.