SCHEMBL16865402

SCHEMBL16865402

CC(=O)OC1(Cc2ccccc2)C(=O)N(C)C(=O)N(c2ccccc2)C1=O

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ELANE P08246 5/20 0.48
ALDH1A1 P00352 4/20 0.47
MAPT P10636 1/20 0.47
PKM P14618 1/20 0.47
ATM Q13315 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16865437 0.90 ALDH1A1 (0.53) ELANEALDH1A1MAPTPKMATM
SCHEMBL16865440 0.88 ELANE (0.46) ELANEALDH1A1MAPTPKMATM
SCHEMBL16865451 0.78 ELANE (0.51) ELANEALDH1A1
SCHEMBL16867610 0.75 ELANE (0.46) ELANEALDH1A1MAPTPKMMEN1
SCHEMBL8805287 0.74 ALDH1A1 (0.65) ELANEALDH1A1MAPTPKMATM
SCHEMBL16865401 0.71 ELANE (0.40) ELANEALDH1A1
SCHEMBL16867611 0.70 ELANE (0.51) ELANEALDH1A1
SCHEMBL16865394 0.70 ELANE (0.41) ELANEALDH1A1MAPTPKMATM
SCHEMBL13879387 0.70 ELANE (0.59) ELANEALDH1A1MEN1KMT2ALMNA
SCHEMBL16865420 0.69 ELANE (0.54) ELANEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND C1R, C1S, C3AR1 ELANE 2715/4885ALDH1A1 2148/4885MAPT 1367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.