SCHEMBL16865451

SCHEMBL16865451

CC(=O)C1(Cc2ccccc2)C(=O)N(C)C(=O)N(c2ccccc2)C1=O

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ELANE P08246 5/20 0.51
ALDH1A1 P00352 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
THPO P40225 1/20 0.39
MAPK1 P28482 1/20 0.37
ITGB2 P05107 1/20 0.36
ICAM1 P05362 1/20 0.36
ITGAL P20701 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35
MT-CO2 P00403 1/20 0.35
ALOX5 P09917 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16867650 0.81 ELANE (0.43) ELANEALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL9726893 0.81 ELANE (0.49) ELANEALDH1A1CYP2C19MAPK1
SCHEMBL16865402 0.78 ELANE (0.48) ELANEALDH1A1
SCHEMBL16865418 0.76 ELANE (0.51) ELANEALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL16865440 0.74 ELANE (0.46) ELANEALDH1A1
SCHEMBL16867611 0.73 ELANE (0.51) ELANEALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL13879387 0.73 ELANE (0.59) ELANEALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL16865420 0.72 ELANE (0.54) ELANEALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL4428745 0.71 ELANE (0.74) ELANEALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL17716270 0.70 ELANE (0.87) ELANEALDH1A1CYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND C1R, C1S, C3AR1 ELANE 2715/4885ALDH1A1 2148/4885CYP1A2 391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.