SCHEMBL16865668

SCHEMBL16865668

CCOc1c(C)cc(C(C)(C)c2cc(C)c(C)c(C)c2)cc1C

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.38
GLA P06280 2/20 0.38
ALDH1A1 P00352 5/20 0.38
HPGD P15428 3/20 0.37
KDM4E B2RXH2 3/20 0.37
GAA P10253 1/20 0.37
HSD17B10 Q99714 1/20 0.37
ESR1 P03372 2/20 0.36
RORC P51449 1/20 0.33
SCN4A P35499 2/20 0.33
TP53 P04637 2/20 0.33
TSHR P16473 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CYP1A2 P05177 1/20 0.33
PPARG P37231 1/20 0.33
HIF1A Q16665 1/20 0.33
VDR P11473 1/20 0.32
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13996167 0.94 ALDH1A1 (0.40) MAPTGLAALDH1A1HPGDKDM4E
SCHEMBL16865673 0.83 NQO1 (0.50) MAPTALDH1A1HPGDTP53TSHR
SCHEMBL19354009 0.82 ALDH1A1 (0.34) MAPTGLAALDH1A1HPGDKDM4E
SCHEMBL12401801 0.81 POLB (0.43) MAPTGLAALDH1A1HPGDKDM4E
SCHEMBL17826411 0.80 THRA (0.47) ALDH1A1KDM4EESR1TSHRMEN1
SCHEMBL16865669 0.80 MEN1 (0.38) MAPTGLAALDH1A1HPGDKDM4E
SCHEMBL16105675 0.78 ESR1 (0.46) ALDH1A1HPGDHSD17B10ESR1TSHR
SCHEMBL12749079 0.76 THRA (0.42) MAPTALDH1A1KDM4EESR1MEN1
SCHEMBL19122375 0.74 ALDH1A1 (0.38) MAPTGLAALDH1A1HPGDKDM4E
SCHEMBL11349119 0.73 LMNA (0.41) MAPTALDH1A1HPGDKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9994673-B2 Bisphenol polyether oligomers, methods of manufacture, and polycarbonates made therefrom SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-06-12 US disclosed
US-20160009859-A1 BISPHENOL POLYETHER OLIGOMERS, METHODS OF MANUFACTURE, AND POLYCARBONATES MADE THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2016-01-14 US disclosed
US-20150183929-A1 BISPHENOL POLYETHER OLIGOMERS, METHODS OF MANUFACTURE, AND POLYCARBONATES MADE THEREFROM SABIC INNOVATIVE PLASTICS IP B.V (NL) 2015-07-02 US disclosed