SCHEMBL16865670

SCHEMBL16865670

CCOc1ccc(C(C)(C)c2ccc(OC(=O)OC)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.49
RAB9A P51151 1/20 0.49
KMT2A Q03164 6/20 0.49
MEN1 O00255 5/20 0.49
CYP1A2 P05177 3/20 0.49
LMNA P02545 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
PLK1 P53350 1/20 0.49
EPHX2 P34913 1/20 0.48
NR1H4 Q96RI1 1/20 0.48
HPGD P15428 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
KDM4E B2RXH2 6/20 0.46
GAA P10253 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
HTT P42858 2/20 0.46
ALDH1A1 P00352 6/20 0.46
TAS1R3 Q7RTX0 1/20 0.46
TAS1R1 Q7RTX1 1/20 0.46
MAPT P10636 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6934422 0.88 ELANE (0.46) NPC1RAB9AKMT2AMEN1LMNA
SCHEMBL11925425 0.88 KMT2A (0.41) KMT2AMEN1CYP1A2LMNATDP1
SCHEMBL18055580 0.84 AR (0.49) NPC1RAB9AKMT2AMEN1CYP1A2
SCHEMBL16405352 0.83 MAPT (0.51) NPC1RAB9AKMT2AMEN1LMNA
SCHEMBL3424216 0.83 MAPT (0.51) NPC1RAB9AKMT2AMEN1LMNA
SCHEMBL26290282 0.83 KMT2A (0.51) NPC1RAB9AKMT2AMEN1PLK1
SCHEMBL13799434 0.82 ESR1 (0.55) KMT2AMEN1LMNATDP1HPGD
SCHEMBL410353 0.82 LMNA (0.48) NPC1RAB9AKMT2AMEN1LMNA
SCHEMBL12313789 0.82 KDM4E (0.51) NPC1RAB9AKMT2AMEN1LMNA
SCHEMBL16405354 0.82 ELANE (0.45) RAB9AKMT2AMEN1LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9994673-B2 Bisphenol polyether oligomers, methods of manufacture, and polycarbonates made therefrom SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-06-12 US disclosed
US-20160009859-A1 BISPHENOL POLYETHER OLIGOMERS, METHODS OF MANUFACTURE, AND POLYCARBONATES MADE THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2016-01-14 US disclosed
US-20150183929-A1 BISPHENOL POLYETHER OLIGOMERS, METHODS OF MANUFACTURE, AND POLYCARBONATES MADE THEREFROM SABIC INNOVATIVE PLASTICS IP B.V (NL) 2015-07-02 US disclosed