Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16868385 | 0.85 | ADRA2B (0.40) | ADRA2BHRH1DRD3 | |
| SCHEMBL6330683 | 0.79 | PDK1 (0.32) | — | |
| SCHEMBL16868386 | 0.71 | ADRA2B (0.70) | ADRA2BHRH1DRD3 | |
| SCHEMBL3380412 | 0.65 | USP2 (0.40) | — | |
| SCHEMBL11352325 | 0.63 | — | — | |
| SCHEMBL24801781 | 0.62 | — | — | |
| SCHEMBL40427 | 0.62 | — | — | |
| SCHEMBL22081189 | 0.61 | — | — | |
| SCHEMBL16401532 | 0.61 | — | — | |
| SCHEMBL14119200 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159477-A1 | PROCESSES FOR PREPARING OXATHIAZIN-LIKE COMPOUNDS | GEISTLICH PHARMA AG (CH) | 2023-05-25 | — | — | US | disclosed |
| US-9844555-B2 | Oxathiazine derivatives as antibacterial and anticancer agents | GEISTLICH PHARMA AG (CH) | 2017-12-19 | — | — | US | disclosed |
| US-20170196876-A1 | OXATHIAZINE DERIVATIVES AS ANTIBACTERIAL AND ANTICANCER AGENTS | GEISTLICH PHARMA AG (CH) | 2017-07-13 | — | — | US | disclosed |
| US-9624187-B2 | Oxathiazine derivatives as antibacterial and anticancer agents | GEISTLICH PHARMA AG (CH) | 2017-04-18 | — | — | US | disclosed |
| US-20160159759-A1 | OXATHIAZINE DERIVATIVES AS ANTIBACTERIAL AND ANTICANCER AGENTS | GEISTLICH PHARMA AG (CH) | 2016-06-09 | — | — | US | disclosed |
| US-9241943-B2 | Oxathiazine derivatives as antibacterial and anticancer agents | GEISTLICH PHARMA AG (CH) | 2016-01-26 | — | — | US | disclosed |
| US-20150182534-A1 | OXATHIAZINE DERIVATIVES AS ANTIBACTERIAL AND ANTICANCER AGENTS | GEISTLICH PHARMA AG (CH) | 2015-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150182534-A1 | OXATHIAZINE DERIVATIVES AS ANTIBACTERIAL AND ANTICANCER AGENTS | OXA1L, TOP2A, HELZ | ADRA2B 4731/4885HRH1 2635/4885DRD3 2953/4885 |
| US-20230159477-A1 | PROCESSES FOR PREPARING OXATHIAZIN-LIKE COMPOUNDS | OXA1L, MAPT, OTC | ADRA2B 4370/4885HRH1 1706/4885DRD3 4055/4885 |
| US-20170196876-A1 | OXATHIAZINE DERIVATIVES AS ANTIBACTERIAL AND ANTICANCER AGENTS | TOP2A, OXA1L, TOP1 | ADRA2B 4660/4885HRH1 2759/4885DRD3 2786/4885 |
| US-20160159759-A1 | OXATHIAZINE DERIVATIVES AS ANTIBACTERIAL AND ANTICANCER AGENTS | TOP2A, OXA1L, TOP1 | ADRA2B 4660/4885HRH1 2759/4885DRD3 2786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.