SCHEMBL16865773

SCHEMBL16865773

CCn1c2ccccc2c2cccc(I)c21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
KDM4E B2RXH2 7/20 0.47
MAPT P10636 5/20 0.47
HTT P42858 4/20 0.47
HSD17B10 Q99714 3/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
HPGD P15428 2/20 0.47
MAPK1 P28482 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
HBB P68871 1/20 0.47
CYP1A2 P05177 1/20 0.45
CYP2C19 P33261 1/20 0.45
PGR P06401 2/20 0.45
LMNA P02545 3/20 0.44
NSD2 O96028 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
NPY5R Q15761 1/20 0.43
PER2 O15055 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14208786 0.83 ALDH1A1 (0.59) ALDH1A1KDM4EMAPTHTTHSD17B10
SCHEMBL17885720 0.81 ALDH1A1 (0.53) ALDH1A1KDM4EMAPTHTTHSD17B10
SCHEMBL27750146 0.81 CNR2 (0.50) ALDH1A1KDM4EMAPTHTTMEN1
SCHEMBL8178240 0.80 ALKBH5 (0.59) ALDH1A1KDM4EMAPTHTTHSD17B10
SCHEMBL15466547 0.79 ALDH1A1 (0.55) ALDH1A1KDM4EMAPTHTTHSD17B10
SCHEMBL29139893 0.79 ALDH1A1 (0.50) ALDH1A1KDM4EMAPTHTTHSD17B10
SCHEMBL27969365 0.79 ALDH1A1 (0.50) ALDH1A1KDM4EMAPTHTTHSD17B10
SCHEMBL30412874 0.79 KDM4E (0.56) ALDH1A1KDM4EMAPTHTTHSD17B10
SCHEMBL3511142 0.79 KDM4E (0.56) ALDH1A1KDM4EMAPTHTTHSD17B10
SCHEMBL9561245 0.79 ALDH1A1 (0.50) ALDH1A1KDM4EMAPTHTTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230371357-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-16 US disclosed
EP-4016656-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND Samsung Electronics Co., Ltd. (KR) 2022-06-22 EP disclosed
US-10396294-B2 Carbazole compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-08-27 US disclosed
US-20150188058-A1 CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-07-02 US disclosed
US-20150188058-A1 CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-07-02 US disclosed
CN-103865524-A Hole-type organic electroluminescent material and application thereof SHAANXI LIGHT OPTOELECTRONICS TECHNOLOGY CO LTD 2014-06-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10396294-B2 Carbazole compound and organic light-emitting device including the same CRY1, CYP1A1, CYP1B1 ALDH1A1 107/4885KDM4E 1622/4885MAPT 2556/4885
US-20150188058-A1 CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CYP1A1, CYP1B1 ALDH1A1 107/4885KDM4E 1622/4885MAPT 2556/4885
US-20230371357-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE L1CAM, CHRM1, FOXM1 ALDH1A1 50/4885KDM4E 3285/4885MAPT 775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.