SCHEMBL16869481

SCHEMBL16869481

COC1C(O)C(O)C(O)C(O)C1OC(=O)c1cccnc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
KMT2A Q03164 7/20 0.50
L3MBTL1 Q9Y468 1/20 0.46
MAPT P10636 1/20 0.44
LMNA P02545 4/20 0.44
THRB P10828 1/20 0.44
APP P05067 1/20 0.44
GAA P10253 1/20 0.44
HCAR3 P49019 1/20 0.44
HCAR2 Q8TDS4 1/20 0.44
ATM Q13315 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
F7 P08709 1/20 0.42
F3 P13726 1/20 0.42
SARM1 Q6SZW1 1/20 0.42
SIRT2 Q8IXJ6 1/20 0.42
SIRT6 Q8N6T7 1/20 0.42
SIRT1 Q96EB6 1/20 0.42
SIRT3 Q9NTG7 1/20 0.42
SIRT5 Q9NXA8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL285309 0.90 ALDH1A1 (0.57) ALDH1A1KMT2AL3MBTL1MAPTLMNA
SCHEMBL1866703 0.90 ALDH1A1 (0.57) ALDH1A1KMT2AL3MBTL1MAPTLMNA
SCHEMBL13580045 0.86 ALDH1A1 (0.57) ALDH1A1KMT2AL3MBTL1MAPTLMNA
Inositol Niacinate SCHEMBL29499769 0.83 ALDH1A1 (0.65) ALDH1A1KMT2AL3MBTL1MAPTLMNA
Inositol Niacinate SCHEMBL13557040 0.83 ALDH1A1 (0.65) ALDH1A1KMT2AL3MBTL1MAPTLMNA
Inositol Niacinate SCHEMBL122591 0.83 ALDH1A1 (0.65) ALDH1A1KMT2AL3MBTL1MAPTLMNA
Inositol Niacinate SCHEMBL122590 0.83 ALDH1A1 (0.65) ALDH1A1KMT2AL3MBTL1MAPTLMNA
SCHEMBL14215313 0.80 TSHR (0.48) ALDH1A1KMT2ALMNAGAATDP1
SCHEMBL14535107 0.77 ALDH1A1 (0.57) ALDH1A1KMT2AL3MBTL1MAPTLMNA
SCHEMBL27105233 0.75 ALDH1A1 (0.54) ALDH1A1KMT2AL3MBTL1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015099362-A1 D-PINITOL PRODRUG AND METHOD FOR PREPARING SAME 제일약품주식회사 2015-07-02 WO disclosed