SCHEMBL285309

SCHEMBL285309

O=C(OC1C(O)C(O)C(O)C(O)C1O)c1cccnc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.57
APP P05067 1/20 0.50
GAA P10253 1/20 0.50
HCAR3 P49019 1/20 0.50
HCAR2 Q8TDS4 1/20 0.50
KMT2A Q03164 6/20 0.49
LMNA P02545 2/20 0.49
ATM Q13315 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
F7 P08709 1/20 0.49
F3 P13726 1/20 0.49
SARM1 Q6SZW1 1/20 0.49
SIRT2 Q8IXJ6 1/20 0.49
SIRT6 Q8N6T7 1/20 0.49
SIRT1 Q96EB6 1/20 0.49
SIRT3 Q9NTG7 1/20 0.49
SIRT5 Q9NXA8 1/20 0.49
SIRT4 Q9Y6E7 1/20 0.49
MAPT P10636 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1866703 0.93 ALDH1A1 (0.57) ALDH1A1APPGAAHCAR3HCAR2
SCHEMBL13580045 0.90 ALDH1A1 (0.57) ALDH1A1APPGAAHCAR3HCAR2
Inositol Niacinate SCHEMBL122590 0.90 ALDH1A1 (0.65) ALDH1A1APPGAAHCAR3HCAR2
Inositol Niacinate SCHEMBL13557040 0.90 ALDH1A1 (0.65) ALDH1A1APPGAAHCAR3HCAR2
Inositol Niacinate SCHEMBL122591 0.90 ALDH1A1 (0.65) ALDH1A1APPGAAHCAR3HCAR2
Inositol Niacinate SCHEMBL29499769 0.90 ALDH1A1 (0.65) ALDH1A1APPGAAHCAR3HCAR2
SCHEMBL16869481 0.90 ALDH1A1 (0.58) ALDH1A1APPGAAHCAR3HCAR2
SCHEMBL14535107 0.83 ALDH1A1 (0.57) ALDH1A1APPGAAHCAR3HCAR2
SCHEMBL27105233 0.81 ALDH1A1 (0.54) ALDH1A1APPGAAHCAR3HCAR2
SCHEMBL3856644 0.78 LGALS9 (0.55) ALDH1A1GAAKMT2ALMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 977 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12605345-B2 Transdermal drug delivery system BioPhysics Pharma, Inc. (US) 2026-04-21 US claimed
US-20250268841-A1 Trans-Epithelial Membrane Drug Delivery System Masiz, John J. (US) 2025-08-28 US claimed
US-20250262233-A1 COMPOSITION SpecNova LLC (US) 2025-08-21 US claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
US-20250120907-A1 Transmucosal Drug Delivery System Masiz, John J. (US) 2025-04-17 US claimed
CN-119792539-A Medicine carrier based on gallic acid-vitamin E polyethylene glycol succinate, micelle, preparation method and application thereof 上海市第一人民医院 2025-04-11 CN claimed
CN-119792545-A Pharmaceutical carrier, micelle, anti-inflammatory and/or anti-atherosclerosis pharmaceutical preparation, and preparation method and application thereof 上海市第一人民医院 2025-04-11 CN claimed
US-12246098-B2 Trans-epithelial membrane drug delivery system BioPhysics Pharma, Inc. (US) 2025-03-11 US claimed
CN-119139248-A Preparation process of inositol nicotinate tablet 吉林显锋科技制药有限公司 2024-12-17 CN claimed
CN-118873522-A Application of isothiocyanate compound 无锡杰西医药股份有限公司 2024-11-01 CN claimed
WO-2006136402-A1 THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS DEVELOGEN AKTIENGESELLSCHAFT (DE) 2006-12-28 WO claimed
CN-1282747-C Preparation method of inositol nicotinate by enzyme method UNIV SOUTH CHINA TECH (CN) 2006-11-01 CN claimed
WO-2006066937-A2 MNK1 OR MNK2 INHIBITORS DEVELOGEN AKTIENGESELLSCHAFT (DE) 2006-06-29 WO claimed
CN-1546676-A Preparation method of inositol nicotinate by enzyme method 华南理工大学 2004-11-17 CN claimed
CN-1494410-A Anhydrous antiperspirant and deodorant compositions containing solid, water-soluble, skin active agent 2004-05-05 CN claimed
WO-2000010610-A2 DRUG TARGETING THERAMARK LIMITED (GB) 2000-03-02 WO claimed
EP-0900563-A1 Production of pharmaceutical formulations containing aescin for treatment of edema and venous disorders Klinge Pharma GmbH (DE) 1999-03-10 EP claimed
CN-1034551-C New use of nicotinic acid and its derivative QIU BOLING (CN) 1997-04-16 CN claimed
EP-0152106-B1 ANTIRHEUMATIC COMPOSITIONS Ismail, Roshdy, Dr. (DE) 1991-09-25 EP claimed
EP-0151987-B1 MEANS FOR THE TREATMENT OF DISEASES OF THE VEINS AND THE ANAL REGION Ismail, Roshdy, Dr. (DE) 1991-05-29 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250262233-A1 COMPOSITION GNG2, DSTN, PRSS12 ALDH1A1 4205/4885APP 3210/4885GAA 1108/4885
US-12605345-B2 Transdermal drug delivery system FABP2, VEGFA, CUTA ALDH1A1 1105/4885APP 1669/4885GAA 3633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.