Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17986261 | 0.81 | IDO1 (0.57) | IDO1ALDH1A1TAAR1MAOBLMNA | |
| SCHEMBL7803807 | 0.76 | IDO1 (0.52) | IDO1ALDH1A1TAAR1MAOBLMNA | |
| SCHEMBL514224 | 0.76 | IDO1 (0.61) | IDO1ALDH1A1TAAR1MAOBLMNA | |
| SCHEMBL5223243 | 0.75 | TAAR1 (0.42) | TAAR1MAOBMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL18339323 | 0.75 | GABRA1 (0.37) | IDO1ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL2714973 | 0.75 | IDO1 (0.67) | IDO1ALDH1A1TAAR1MAOBLMNA | |
| SCHEMBL31065556 | 0.75 | IDO1 (0.67) | IDO1ALDH1A1TAAR1MAOBLMNA | |
| SCHEMBL17986361 | 0.75 | IDO1 (0.50) | IDO1ALDH1A1TAAR1MAOBLMNA | |
| SCHEMBL17986360 | 0.75 | IDO1 (0.50) | IDO1ALDH1A1TAAR1MAOBLMNA | |
| SCHEMBL25923618 | 0.75 | IDO1 (0.50) | IDO1ALDH1A1TAAR1MAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1299365-A | Hygromycin A derivatives | PFIZER PROD INC (US) | 2001-06-13 | — | — | CN | claimed |
| CN-1299367-A | 2' -deoxy hygromycin derivatives | PFIZER PROD INC (US) | 2001-06-13 | — | — | CN | claimed |
| US-20170000132-A1 | BENZOXABOROLE FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-01-05 | — | — | US | disclosed |
| US-20170000132-A1 | BENZOXABOROLE FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-01-05 | — | — | US | disclosed |
| WO-2015097237-A1 | BENZOXABOROLE FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-07-02 | — | — | WO | disclosed |
| CN-1299365-A | Hygromycin A derivatives | PFIZER PROD INC (US) | 2001-06-13 | — | — | CN | disclosed |
| CN-1299367-A | 2' -deoxy hygromycin derivatives | PFIZER PROD INC (US) | 2001-06-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170000132-A1 | BENZOXABOROLE FUNGICIDES | CYP4X1, BROX, CYP1B1 | IDO1 893/4885ALDH1A1 1143/4885TAAR1 2883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.