Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27978533 | 0.86 | LMNA (0.46) | PPARGFPR2TRPM2ALDH1A1MAPT | |
| SCHEMBL14821764 | 0.81 | POLB (0.46) | PPARGALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL16867095 | 0.81 | ALDH1A1 (0.48) | PPARGALDH1A1MAPTLMNANPSR1 | |
| Bromide SCHEMBL11028063 | 0.80 | POLB (0.45) | PPARGALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL22519187 | 0.79 | KDM4E (0.43) | TP53ALDH1A1MAPTCYP2C19CYP1A2 | |
| SCHEMBL22074459 | 0.77 | POLB (0.47) | PPARGALDH1A1MAPTLMNACYP2C9 | |
| Bromide SCHEMBL7918168 | 0.77 | PPARG (0.44) | PPARGALDH1A1MAPTLMNAPOLB | |
| Bromide SCHEMBL16648412 | 0.74 | ALDH1A1 (0.36) | TP53ALDH1A1MAPTLMNACYP2C19 | |
| SCHEMBL3576418 | 0.72 | KDM4E (0.51) | ALDH1A1MAPTLMNANPSR1CYP2C9 | |
| Bromide SCHEMBL3576414 | 0.71 | KDM4E (0.50) | ALDH1A1MAPTLMNANPSR1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9271500-B2 | Fused heterocyclic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-03-01 | — | — | US | disclosed |
| US-20150181880-A1 | FUSED HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150181880-A1 | FUSED HETEROCYCLIC COMPOUND | C5, CYC1, CYP1A1 | PPARG 2121/4885FPR2 431/4885TRPM2 3789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.