SCHEMBL168712

SCHEMBL168712

O=CCc1ccccc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 5/20 0.50
PNMT P11086 1/20 0.50
TAAR1 Q96RJ0 5/20 0.46
RAB9A P51151 2/20 0.45
NPC1 O15118 1/20 0.45
CHRM2 P08172 1/20 0.45
SMN1; SMN2 Q16637 4/20 0.42
LMNA P02545 4/20 0.42
HTT P42858 3/20 0.42
PKM P14618 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
RECQL P46063 1/20 0.41
TSHR P16473 1/20 0.41
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30801131 1.00 IDO1 (0.50) IDO1PNMTTAAR1RAB9ANPC1
SCHEMBL1515825 0.83 DPP4 (0.57) IDO1PNMTTAAR1RAB9ANPC1
SCHEMBL6194272 0.82 PNMT (0.56) IDO1PNMTTAAR1SMN1; SMN2MEN1
SCHEMBL7461135 0.82 TDP1 (0.38) PNMTSMN1; SMN2LMNAHTTMEN1
SCHEMBL5240860 0.79 CYP1A2 (0.52) IDO1PNMTTAAR1LMNAMEN1
SCHEMBL2318046 0.79 HSP90AA1 (0.49) PNMTRAB9ANPC1SMN1; SMN2MEN1
SCHEMBL22394576 0.79 PNMT (0.42) IDO1PNMTTAAR1SMN1; SMN2LMNA
SCHEMBL2556542 0.79 ALDH1A1 (0.40) IDO1PNMTTAAR1HTTMEN1
SCHEMBL5530787 0.79 ALDH1A1 (0.42) PNMTLMNAMEN1KMT2AALDH1A1
SCHEMBL13824528 0.79 TAAR1 (0.45) IDO1PNMTTAAR1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 301 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111808100-A Indole alkaloid compound and preparation method and application thereof 广州中医药大学(广州中医药研究院) 2020-10-23 CN claimed
CN-107686475-A 2,3,5 3 substituted thiophenes, derivative and its synthetic method 湘潭大学 2018-02-13 CN claimed
EP-1854160-A2 REDOX-ACTIVE STRUCTURES AND DEVICES UTILIZING THE SAME YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 2007-11-14 EP claimed
WO-2006085319-A2 REDOX-ACTIVE STRUCTURES AND DEVICES UTILIZING THE SAME YEDA RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) 2006-08-17 WO claimed
US-20020048774-A1 Liquid phase parallel synthesis of chemical libraries BRISTOL-MYERS SQUIBB PHARMA RESEARCH LABS, INC. 2002-04-25 US claimed
US-6245937-B1 COMBINATORIAL LIBRARIES OF CHEMICAL COMPOUNDS SYNTHESIZED BY BIPHASIC SYNTHESIS UTILIZING SPECIFIED TEMPLATES DUPONT PHARMACEUTICALS RESEARCH LABORATORIES, INC. 2001-06-12 US claimed
US-11896593-B2 Sulfamate derivative compounds for use in treating or alleviating a psychiatric disorder BIO-PHARM SOLUTIONS CO., LTD. (KR) 2024-02-13 US disclosed
WO-2023210623-A1 HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME 株式会社エス・ディー・エス バイオテック 2023-11-02 WO disclosed
US-20230324789-A1 PHOTOSENSITIVE RESIN COMPOSITION, PERMANENT RESIST, METHOD FOR FORMING PERMANENT RESIST, AND METHOD FOR INSPECTING PERMANENT RESIST CURED FILM RESONAC CORPORATION (JP) 2023-10-12 US disclosed
WO-2023193070-A1 PAN-CHEMOKINE ANTAGONISTS FOR USE IN TREATING CANCER AND IMMUNE DISORDERS "MICAR INNOVATION" LTD. (BG) 2023-10-12 WO disclosed
CN-110582726-B Positive photosensitive resin composition, thermal crosslinking agent for positive photosensitive resin, pattern cured film, method for producing pattern cured film, semiconductor element, and electronic device 株式会社力森诺科 2023-08-04 CN disclosed
EP-4211125-A1 SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING A PSYCHIATRIC DISORDER Bio-Pharm Solutions Co., Ltd. (KR) 2023-07-19 EP disclosed
CN-116234798-A Sulfamate derivative compounds for the treatment or alleviation of psychotic disorders 生物药品解决方案有限公司 2023-06-06 CN disclosed
US-4364952-A Certain 1,4-dihydro-2,6-dimethyl-3,5-pyridine-dicarboxylates, composition containing same and method of use BAYER AKTIENGESELLSCHAFT (DE) 1982-12-21 US disclosed
US-4338467-A IN THE PRESENCE OF A COBALT CATALYST AND A NITRILE SOLVENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-07-06 US disclosed
EP-0042093-A2 4-Aralkyl-1,4-dihydropyridines, processes for praparing them, their use as medicines and preparation thereof BAYER AG (DE) 1981-12-23 EP disclosed
EP-0034430-A1 Process for preparing arylacetaldehydes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-08-26 EP disclosed
US-4267359-A Novel carboxylic acid esters ZOECON CORPORATION (US) 1981-05-12 US disclosed
EP-0024348-A1 Substituted 6-Phenethyl-and phenylethenyl-3,4,5,6-tetrahydro-4-hydroxytetraydropyran-2-ones in the4-R trans stereoisomeric forms and the corresponding dihydroxy acids, process for preparing and pharmaceutical composition comprising them MERCK & CO. INC. (US) 1981-03-04 EP disclosed
US-4204071-A 4-Aryl-3-butenoic acids and lower alkyl esters ZOECON CORPORATION (US) 1980-05-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020048774-A1 Liquid phase parallel synthesis of chemical libraries CDK2, CDC25C, POLR2H IDO1 1450/4885PNMT 989/4885TAAR1 3279/4885
US-11896593-B2 Sulfamate derivative compounds for use in treating or alleviating a psychiatric disorder SLC6A4, SLC6A3, SLC6A2 IDO1 312/4885PNMT 203/4885TAAR1 379/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.