Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.52 |
| ▸ | NSD2 | O96028 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4646790 | 0.89 | NSD2 (0.48) | GPR119NSD2ALDH1A1NPC1MAPT | |
| SCHEMBL18425256 | 0.88 | ALDH1A1 (0.56) | GPR119ALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL3107643 | 0.85 | ALDH1A1 (0.50) | GPR119ALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL28331009 | 0.84 | GPR119 (0.37) | GPR119NSD2 | |
| SCHEMBL16876736 | 0.84 | L3MBTL1 (0.50) | GPR119NSD2ALDH1A1NPC1MAPT | |
| SCHEMBL15410448 | 0.84 | ALDH1A1 (0.49) | GPR119NSD2ALDH1A1NPC1MAPT | |
| SCHEMBL4647276 | 0.83 | ALDH1A1 (0.50) | GPR119NSD2ALDH1A1NPC1MAPT | |
| SCHEMBL4434545 | 0.82 | ALDH1A1 (0.50) | GPR119NSD2ALDH1A1NPC1MAPT | |
| SCHEMBL4648718 | 0.82 | ALDH1A1 (0.49) | GPR119NSD2ALDH1A1NPC1MAPT | |
| SCHEMBL4647099 | 0.82 | ALDH1A1 (0.51) | GPR119ALDH1A1NPC1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092228-A1 | TRPA1 MODULATORS | Algomedix, Inc. (US) | 2016-11-16 | — | — | EP | disclosed |
| WO-2015103060-A1 | TRPA1 MODULATORS | ALGOMEDIX, INC. (US) | 2015-07-09 | — | — | WO | disclosed |