Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16876928 | 0.77 | LMNA (0.33) | DUT | |
| SCHEMBL13504282 | 0.77 | FKBP1A (0.32) | — | |
| SCHEMBL23611963 | 0.77 | FKBP1A (0.32) | — | |
| SCHEMBL28714010 | 0.77 | FKBP1A (0.32) | — | |
| SCHEMBL490362 | 0.76 | PPM1D (0.30) | — | |
| SCHEMBL3577011 | 0.76 | PPM1D (0.30) | — | |
| SCHEMBL19945733 | 0.76 | PPM1D (0.30) | — | |
| SCHEMBL17888678 | 0.76 | DUT (0.33) | DUT | |
| SCHEMBL3577005 | 0.76 | SMYD2 (0.40) | — | |
| SCHEMBL30829443 | 0.73 | DUT (0.31) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092229-A1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | Bristol-Myers Squibb Company (US) | 2016-11-16 | — | — | EP | disclosed |
| WO-2015103509-A1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-07-09 | — | — | WO | disclosed |