Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA7 | P43166 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30360640 | 1.00 | CA2 (0.48) | CA2CA12CA1CA7CA9 | |
| Formic Acid SCHEMBL27768982 | 0.89 | TSHR (0.47) | CA2CA12CA1CA7CA9 | |
| SCHEMBL1823391 | 0.85 | PDE4A (0.48) | TSHRALDH1A1MAPK1PDE4APDE4B | |
| SCHEMBL5027104 | 0.85 | PDE4B (0.40) | CA2CA12CA1CA7CA9 | |
| SCHEMBL23375945 | 0.85 | KDM4E (0.54) | TSHRALDH1A1MAPK1PDE4APDE4B | |
| SCHEMBL14658523 | 0.85 | ALDH1A1 (0.40) | CA2CA12CA1CA7CA9 | |
| SCHEMBL16641175 | 0.83 | CA2 (0.54) | CA2CA12CA1CA7CA9 | |
| SCHEMBL31004959 | 0.83 | PDE4B (0.43) | ARTSHRALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL31273968 | 0.83 | AR (0.44) | ACHEARALDH1A1CYP1A2GAK | |
| SCHEMBL21880260 | 0.83 | ALDH1A1 (0.40) | CA2CA12CA1CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118638088-B | Preparation method for synthesizing flavonoid compounds based on carbon dioxide and alkyne | 湖南工程学院 | 2024-11-22 | — | — | CN | claimed |
| CN-118515716-A | NNN-pyridine-quinoline cobalt complex, preparation method and catalytic alkyne hydrosilylation reaction | 石河子大学 | 2024-08-20 | — | — | CN | claimed |
| CN-114874088-A | Acetylenic acid and preparation method thereof | 中国科学院上海高等研究院 | 2022-08-09 | — | — | CN | claimed |
| EP-3050871-B1 | NOVEL BIS-AMIDE DERIVATIVE AND USE THEREOF | UNIV INDUSTRY COOPERATION GROUP KYUNG HEE UNIV (KR) | 2018-11-07 | — | — | EP | claimed |
| CN-107011162-A | A kind of method that α acyloxy ketone compounds are prepared with end group acetylene compound | 湖南理工学院 | 2017-08-04 | — | — | CN | claimed |
| CN-104529725-B | The preparation method of perfluoro octyl sulfonic acid silver catalysis alkynes hydrolysis ketone | 湖南大学 | 2016-06-08 | — | — | CN | claimed |
| CN-104529725-A | Method for synthesizing ketone through catalyzing and hydrolyzing alkyne with silver perfluorooctanesulfonate | UNIV HUNAN | 2015-04-22 | — | — | CN | claimed |
| EP-1601674-B1 | Hydroxyalkyl substituted 1,3,8-triazaspiro[4.5]decan-4-one derivatives useful for the treatment of ORL-1 receptor mediated disorders | JANSSEN PHARMACEUTICA NV (BE) | 2012-08-08 | — | — | EP | claimed |
| EP-1620399-B1 | INDOLONE-ACETAMIDE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB PHARMA SA (BE) | 2010-09-22 | — | — | EP | claimed |
| EP-1551834-B1 | SUBSTITUTED QUINAZOLINONE COMPOUNDS | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2010-08-25 | — | — | EP | claimed |
| EP-1023301-B1 | A HETEROCYCLIC CHEMICAL COMPOUND | BIONERIS AB (SE) | 2003-04-09 | — | — | EP | claimed |
| EP-0557526-B1 | PYRROLOAZEPINE COMPOUND | SUNTORY LTD (JP) | 2003-04-02 | — | — | EP | claimed |
| EP-1056759-B1 | 2-(PURIN-9-YL) -TETRAHYDROFURAN-3, 4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-09-04 | — | — | EP | claimed |
| EP-0970090-B1 | SUBSTITUTED 4-ARYLMETHYLENE-2-IMINO-2,3-DIHYDROTHIAZOLES AND DERIVATIVES AND THEIR PHARMACEUTICAL USE | KNOLL GMBH (DE) | 2002-06-05 | — | — | EP | claimed |
| EP-0544152-B1 | Herbicidal quinoline-3-carbonamides | BASF AG (DE) | 1996-09-11 | — | — | EP | claimed |
| EP-0567967-B1 | Tritium-labelled fibrinogen-receptor-antagonists, their use and their production | THOMAE GMBH DR K (DE) | 1996-07-10 | — | — | EP | claimed |
| EP-0278453-B1 | 2,4- and 2,5-Pyridine-dicarboxylic-acid derivatives, process for their preparation, their use and medicines based on these compounds | HOECHST AG (DE) | 1994-12-28 | — | — | EP | claimed |
| EP-0587823-A1 | USING THE IMMUNOACTIVATING ACTIVITY OF 3-NAPHTHYLOXY-2-HYDROXY-PROPYLAMINES, IN PARTICULAR FOR PROVIDING CELL IMMUNITY, E.G. AGAINST VIRAL INFECTIONS | PEUSCHEL, Karin, Elisabeth (CH) | 1994-03-23 | — | — | EP | claimed |
| WO-1993013049-A1 | USING THE IMMUNOACTIVATING ACTIVITY OF 3-NAPHTHYLOXY-2-HYDROXY-PROPYLAMINES, IN PARTICULAR FOR PROVIDING CELL IMMUNITY, E.G. AGAINST VIRAL INFECTIONS | PEUSCHEL KARIN ELISABETH (CH) | 1993-07-08 | — | — | WO | claimed |
| EP-0155079-B1 | ACETYLENE AMINES AND THEIR USE AS VASODILATORS AND ANTIHYPERTENSIVES | McNeilab, Inc. (US) | 1988-02-17 | — | — | EP | claimed |