SCHEMBL30360640

SCHEMBL30360640

C#Cc1ccc(OC)c(OC)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.48
CA12 O43570 3/20 0.48
CA1 P00915 3/20 0.48
CA7 P43166 3/20 0.48
CA9 Q16790 3/20 0.48
CA14 Q9ULX7 3/20 0.48
ACHE P22303 1/20 0.48
AR P10275 3/20 0.43
TSHR P16473 3/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
POLB P06746 1/20 0.42
MAPK1 P28482 1/20 0.42
PDE4A P27815 2/20 0.41
CA4 P22748 2/20 0.41
NR3C1 P04150 1/20 0.41
CA6 P23280 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL168783 1.00 CA2 (0.48) CA2CA12CA1CA7CA9
Formic Acid SCHEMBL27768982 0.89 TSHR (0.47) CA2CA12CA1CA7CA9
SCHEMBL1823391 0.85 PDE4A (0.48) TSHRALDH1A1MAPK1PDE4APDE4B
SCHEMBL5027104 0.85 PDE4B (0.40) CA2CA12CA1CA7CA9
SCHEMBL23375945 0.85 KDM4E (0.54) TSHRALDH1A1MAPK1PDE4APDE4B
SCHEMBL14658523 0.85 ALDH1A1 (0.40) CA2CA12CA1CA7CA9
SCHEMBL16641175 0.83 CA2 (0.54) CA2CA12CA1CA7CA9
SCHEMBL31004959 0.83 PDE4B (0.43) ARTSHRALDH1A1CYP1A2CYP2C9
SCHEMBL31273968 0.83 AR (0.44) ACHEARALDH1A1CYP1A2GAK
SCHEMBL21880260 0.83 ALDH1A1 (0.40) CA2CA12CA1CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120117999-A Fluorotranilast derivatives and medical application thereof 中国药科大学 2025-06-10 CN disclosed
WO-2023237732-A1 RSV INHIBITING TRIAZOLO BEARING DERIVATIVES Janssen Sciences Ireland Unlimited Company (IE) 2023-12-14 WO disclosed
CN-111511744-B Diazaindole compounds 百时美施贵宝公司 2023-09-22 CN disclosed
CN-115956077-A Substituted heteroaryl compounds as TLR9 inhibitors 百时美施贵宝公司 2023-04-11 CN disclosed
CN-115867549-A 1H-pyrrolo [3,2-c ] pyridine and 1H-pyrrolo [2,3-c ] pyridine derivatives as TLR9 inhibitors for the treatment of fibrosis 百时美施贵宝公司 2023-03-28 CN disclosed