Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 8/20 | 0.48 |
| ▸ | KLK1 | P06870 | 8/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16880649 | 0.88 | KMT2A (0.47) | KLKB1KLK1ATMNAMPTALDH1A1 | |
| SCHEMBL16881474 | 0.85 | RECQL (0.49) | KLKB1KLK1RECQLCYP2C9CYP2C19 | |
| SCHEMBL16881118 | 0.84 | LOXL2 (0.59) | KLKB1KLK1ATMCYP11B1CYP11B2 | |
| SCHEMBL30675668 | 0.81 | ATM (0.50) | ATMCYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL26961945 | 0.81 | ATM (0.50) | ATMCYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL23120562 | 0.81 | ATM (0.53) | KLKB1KLK1ATMCYP11B1CYP11B2 | |
| SCHEMBL22253411 | 0.79 | LOXL2 (0.62) | CYP2C9CYP2C19CA12CA1CA2 | |
| SCHEMBL16881389 | 0.79 | ATM (0.44) | KLKB1KLK1ATMCYP11B1CYP11B2 | |
| SCHEMBL16880998 | 0.79 | SMN1; SMN2 (0.51) | ATMALDH1A1 | |
| SCHEMBL16881124 | 0.77 | ATM (0.46) | KLKB1KLK1ATMCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061480-B | Therapeutic inhibitory compounds | 莱福斯希医药公司 | 2020-02-28 | — | — | CN | disclosed |
| EP-3089746-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | Lifesci Pharmaceuticals, Inc. (BB) | 2016-11-09 | — | — | EP | disclosed |
| WO-2015103317-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2015-07-09 | — | — | WO | disclosed |