Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.46 |
| ▸ | KLK1 | P06870 | 4/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16880735 | 0.88 | KLKB1 (0.48) | ATMKLKB1KLK1ALDH1A1NAMPT | |
| SCHEMBL16880998 | 0.87 | SMN1; SMN2 (0.51) | KMT2AATMALDH1A1POLBMAPT | |
| SCHEMBL16880811 | 0.87 | ATM (0.42) | ATMKLKB1KLK1POLB | |
| SCHEMBL16881310 | 0.86 | KMT2A (0.60) | KMT2AKLKB1KLK1HDAC1HDAC6 | |
| SCHEMBL16891565 | 0.85 | KMT2A (0.48) | KMT2AKLKB1KLK1HDAC1HDAC6 | |
| SCHEMBL16881118 | 0.82 | LOXL2 (0.59) | ATMKLKB1KLK1ALDH1A1MAPT | |
| SCHEMBL30675668 | 0.82 | ATM (0.50) | KMT2AATMALDH1A1POLBMAPT | |
| SCHEMBL26961945 | 0.82 | ATM (0.50) | KMT2AATMALDH1A1POLBMAPT | |
| SCHEMBL23120562 | 0.82 | ATM (0.53) | ATMKLKB1KLK1ALDH1A1RAB9A | |
| SCHEMBL16881190 | 0.82 | ATM (0.42) | ATMKLKB1KLK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061480-B | Therapeutic inhibitory compounds | 莱福斯希医药公司 | 2020-02-28 | — | — | CN | disclosed |
| EP-3089746-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | Lifesci Pharmaceuticals, Inc. (BB) | 2016-11-09 | — | — | EP | disclosed |
| CN-106061480-A | Therapeutic inhibitory compounds | 莱福斯希医药公司 | 2016-10-26 | — | — | CN | disclosed |
| WO-2015103317-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2015-07-09 | — | — | WO | disclosed |