Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | F13A1 | P00488 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16880649 | 0.87 | KMT2A (0.47) | ALDH1A1MAPTATMKMT2APOLB | |
| SCHEMBL16881056 | 0.87 | KDM4E (0.50) | SMN1; SMN2KDM4EF13A1MTNR1AMTNR1B | |
| SCHEMBL30675668 | 0.80 | ATM (0.50) | ALDH1A1LMNAMAPTATMKMT2A | |
| SCHEMBL16881118 | 0.80 | LOXL2 (0.59) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL26961945 | 0.80 | ATM (0.50) | ALDH1A1LMNAMAPTATMKMT2A | |
| SCHEMBL23120562 | 0.80 | ATM (0.53) | ALDH1A1LMNAHPGDHIF1AATM | |
| SCHEMBL16880811 | 0.80 | ATM (0.42) | ATMPOLB | |
| SCHEMBL14966449 | 0.79 | SMN1; SMN2 (0.68) | SMN1; SMN2KDM4EF13A1ALDH1A1LMNA | |
| SCHEMBL16880735 | 0.79 | KLKB1 (0.48) | ALDH1A1ATM | |
| SCHEMBL16881233 | 0.78 | ACACB (0.50) | ATMACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3089746-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | Lifesci Pharmaceuticals, Inc. (BB) | 2016-11-09 | — | — | EP | disclosed |
| WO-2015103317-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2015-07-09 | — | — | WO | disclosed |