Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1744064 | 0.91 | LMNA (0.44) | LMNACYP2C19HIF1A | |
| SCHEMBL16883242 | 0.89 | LMNA (0.49) | LMNACYP2C19HIF1A | |
| SCHEMBL2533624 | 0.89 | LMNA (0.42) | LMNACYP2C19HIF1A | |
| SCHEMBL1742159 | 0.87 | LMNA (0.42) | LMNACYP2C19HIF1A | |
| SCHEMBL19261521 | 0.86 | LMNA (0.41) | LMNACYP2C19HIF1A | |
| SCHEMBL19261495 | 0.85 | LMNA (0.40) | LMNACYP2C19HIF1A | |
| SCHEMBL13283944 | 0.83 | LMNA (0.39) | LMNACYP2C19HIF1A | |
| SCHEMBL16883240 | 0.83 | LMNA (0.54) | LMNACYP2C19HIF1A | |
| SCHEMBL2764317 | 0.83 | LMNA (0.48) | LMNACYP2C19HIF1A | |
| SCHEMBL2764066 | 0.81 | LMNA (0.46) | LMNACYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150191422-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2015-07-09 | — | — | US | disclosed |
| US-20150191422-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2015-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150191422-A1 | CONTRAST AGENTS | SSTR3, INSR, INSRR | LMNA 1656/4885CYP2C19 3523/4885HIF1A 1391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.