Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.49 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896434 | 0.89 | HSD17B10 (0.67) | KMT2AHSD17B10CYP4A11CYP4F2LMNA | |
| SCHEMBL22922181 | 0.88 | CYP4F2 (0.59) | KMT2AHSD17B10CYP4A11CYP4F2F2RL1 | |
| SCHEMBL8658445 | 0.86 | HSD17B10 (0.58) | KMT2AHSD17B10CYP4A11CYP4F2EPHX2 | |
| SCHEMBL2499088 | 0.85 | CYP4A11 (0.64) | HSD17B10CYP4A11CYP4F2ADRB2ADRB1 | |
| SCHEMBL2570247 | 0.85 | ALDH1A1 (0.52) | KMT2ACYP4A11CYP4F2F2RL1ADRB2 | |
| SCHEMBL5012302 | 0.84 | PARP10 (0.48) | CYP4A11CYP4F2F2RL1ADRB2ADRB1 | |
| SCHEMBL4123759 | 0.84 | CYP4A11 (0.47) | KMT2AHSD17B10CYP4A11CYP4F2F2RL1 | |
| SCHEMBL7280993 | 0.83 | HDAC1 (0.46) | KMT2AHSD17B10MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL6847256 | 0.82 | CYP4F2 (0.70) | KMT2AHSD17B10CYP4A11CYP4F2LMNA | |
| SCHEMBL11243916 | 0.81 | CYP4F2 (0.58) | KMT2AHSD17B10CYP4A11CYP4F2F2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027965-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |
| WO-2012027965-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |