SCHEMBL168873

SCHEMBL168873

CCc1cccc(CC)c1N=C=Nc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.58
GABRB2 P47870 4/20 0.58
MIF P14174 1/20 0.38
CLCN2 P51788 1/20 0.33
TP53 P04637 1/20 0.32
KCNK3 O14649 1/20 0.32
KCNK9 Q9NPC2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
MGLL Q99685 1/20 0.32
GSK3B P49841 1/20 0.31
PDK2 Q15119 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL159089 0.88 GABRA1 (0.72) GABRA1GABRB2ALDH1A1LMNAMGLL
SCHEMBL159754 0.81 GABRA1 (0.41) GABRA1GABRB2MIFCLCN2ALDH1A1
SCHEMBL11424944 0.77 GABRA1 (0.57) GABRA1GABRB2TP53ALDH1A1LMNA
SCHEMBL156364 0.77 GABRA1 (0.57) GABRA1GABRB2MAPT
SCHEMBL11416607 0.75 GABRA1 (0.55) GABRA1GABRB2LMNA
SCHEMBL156948 0.74 MIF (0.60) MIFALDH1A1LMNAMAPT
SCHEMBL28295657 0.74 CYP3A4 (0.38) GABRA1GABRB2MIFALDH1A1
SCHEMBL722841 0.74 GABRA1 (0.47) GABRA1GABRB2TP53ALDH1A1MAPT
SCHEMBL18258702 0.74 GABRA1 (0.52) GABRA1GABRB2
SCHEMBL1457739 0.74 GABRA1 (1.00) GABRA1GABRB2ALDH1A1LMNAMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8921465-B2 Polybutylene terephthalate resin composition WINTECH POLYMER LTD. (JP) 2014-12-30 US disclosed
US-20130203905-A1 POLYBUTYLENE TEREPHTHALATE RESIN COMPOSITION WINTECH POLYMER LTD. (JP) 2013-08-08 US disclosed
EP-2578633-A1 POLYBUTYLENE TEREPHTHALATE RESIN COMPOSITION Wintech Polymer Ltd. (JP) 2013-04-10 EP disclosed
EP-1486536-B2 FLAME-RETARDANT RESIN COMPOSITION POLYPLASTICS CO (JP) 2012-10-10 EP disclosed
US-20120083553-A1 Molded Articles For Electric Vehicle Parts Win-Tech Polymer Ltd. (JP) 2012-04-05 US disclosed
EP-1452567-B1 FLAME-RETARDANT RESIN COMPOSITION POLYPLASTICS CO (JP) 2012-03-07 EP disclosed
EP-1466946-B1 FLAME-RETARDANT RESIN COMPOSITION POLYPLASTICS CO (JP) 2011-11-09 EP disclosed
US-7498375-B2 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2009-03-03 US disclosed
US-7205346-B2 halogen-free, fireproof mixture of thermoplastic resins, containing phosphorus compounds, aromatic resins, nitrogen compounds, metal compounds, stabilizer agents and water repellants POLYPLASTICS CO., LTD. (JP) 2007-04-17 US disclosed
EP-1486536-B1 FLAME-RETARDANT RESIN COMPOSITION POLYPLASTICS CO (JP) 2007-01-24 EP disclosed
US-7115677-B2 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2006-10-03 US disclosed
US-20050004292-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2005-01-06 US disclosed
US-20040266916-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2004-12-30 US disclosed
US-20040254270-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2004-12-16 US disclosed
EP-1486536-A1 FLAME-RETARDANT RESIN COMPOSITION Polyplastics Co Ltd (JP) 2004-12-15 EP disclosed
EP-1466946-A1 FLAME-RETARDANT RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2004-10-13 EP disclosed
EP-1452567-A1 FLAME-RETARDANT RESIN COMPOSITION Polyplastics Co Ltd (JP) 2004-09-01 EP disclosed