SCHEMBL159089

SCHEMBL159089

CCc1cccc(CC)c1N=C=Nc1c(CC)cccc1CC

nearest known ligand 0.72

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.72
GABRB2 P47870 4/20 0.72
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
SCN5A Q14524 4/20 0.35
CACNA1C Q13936 3/20 0.35
KCNH2 Q12809 2/20 0.35
HTR1A P08908 2/20 0.34
DRD2 P14416 2/20 0.34
DRD4 P21917 2/20 0.34
HTR2A P28223 2/20 0.34
HTR2C P28335 2/20 0.34
DRD3 P35462 2/20 0.34
PDK2 Q15119 2/20 0.33
MGLL Q99685 1/20 0.33
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL168873 0.88 GABRA1 (0.58) GABRA1GABRB2ALDH1A1LMNAPDK2
SCHEMBL156364 0.87 GABRA1 (0.57) GABRA1GABRB2HTR1ADRD2DRD4
SCHEMBL11424944 0.87 GABRA1 (0.57) GABRA1GABRB2ALDH1A1LMNASCN5A
SCHEMBL11416607 0.85 GABRA1 (0.55) GABRA1GABRB2LMNAHTR2CCYP3A4
SCHEMBL1457739 0.84 GABRA1 (1.00) GABRA1GABRB2ALDH1A1LMNASCN5A
SCHEMBL18258702 0.84 GABRA1 (0.52) GABRA1GABRB2KCNH2HTR1A
SCHEMBL959941 0.82 GABRA1 (0.52) GABRA1GABRB2ALDH1A1LMNAHTR2C
SCHEMBL2316422 0.82 GABRA1 (0.67) GABRA1GABRB2ALDH1A1LMNASCN5A
SCHEMBL1457256 0.82 GABRA1 (1.00) GABRA1GABRB2ALDH1A1LMNAHTR1A
SCHEMBL10613392 0.80 GABRA1 (0.81) GABRA1GABRB2ALDH1A1LMNASCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180134947-A1 METHODS FOR TREATING HIGH TEMPERATURE SUBTERRANEAN FORMATIONS SCHLUMBERGER TECHNOLOGY CORPORATION 2018-05-17 US claimed
WO-2017163258-A1 PROCESS FOR THE PREPARATION OF N-[6-(CIS-2,6-DIMETHYLMORPHOLIN-4-YL)PYRIDINE-3-YL]-2- METHYL-4'-(TRIFIUOROMETHOXY) [1,1' -BIPHENYI]-3-CARBOXAMIDE AND ITS POLYMORPHS THEREOF MSN LABORATORIES PRIVATE LIMITED (IN) 2017-09-28 WO claimed
WO-2016159817-A1 METHODS FOR TREATING HIGH TEMPERATURE SUBTERRANEAN FORMATIONS SCHLUMBERGER CANADA LIMITED (CA) 2016-10-06 WO claimed
US-8247156-B2 Processes for producing polyester latexes with improved hydrolytic stability XEROX CORPORATION (US) 2012-08-21 US claimed
US-20120064453-A1 PROCESSES FOR PRODUCING POLYESTER LATEXES WITH IMPROVED HYDROLYTIC STABILITY XEROX CORPORATION (US) 2012-03-15 US claimed
WO-2011033366-A8 IMPROVED PROCESS FOR THE PREPARATION OF DULOXETINE AND ITS PHARMACEUTICALLY ACCEPTABLE SALT JUBILANT LIFE SCIENCES LIMITED (IN) 2011-05-05 WO claimed
WO-2011033366-A2 PROCESS FOR THE PREPARATION OF DULOXETINE HYDROCHLORIDE AND ITS PRECURSORS JUBILANT LIFE SCIENCES LIMITED (IN) 2011-03-24 WO claimed
US-12559624-B2 Film comprising polylactic acid polymer suitable for graphic articles 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-02-24 US disclosed
CN-120153026-A Biodegradable polymer composition 巴斯夫欧洲公司 2025-06-13 CN disclosed
US-20240294748-A1 FILM COMPRISING POLYLACTIC ACID POLYMER SUITABLE FOR GRAPHIC ARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-09-05 US disclosed
US-12065531-B2 Polyglycolic acid resin and production process thereof PUJING CHEMICAL INDUSTRY CO., LTD. (CN) 2024-08-20 US disclosed
EP-4400529-A1 SEMI-AROMATIC POLYETHER ESTER, PREPARATION METHOD THEREFOR AND USE THEREOF Zhuhai Wango Chemical Co., Ltd. (CN) 2024-07-17 EP disclosed
EP-4400527-A1 SEMI-AROMATIC POLYESTER, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Zhuhai Wango Chemical Co., Ltd. (CN) 2024-07-17 EP disclosed
US-4929656-A CARBODIIMIDE AND GUANIDINE DERIVATIVES HOECHST CELANESE CORPORATION (US) 1990-05-29 US disclosed
EP-0357193-A2 Blends of copolyester elastomers carbodiimides and thermoplastic polymers HOECHST CELANESE CORPORATION (US) 1990-03-07 EP disclosed
EP-0357194-A1 Blends of copolyester elastomers and carbodiimides HOECHST CELANESE CORPORATION (US) 1990-03-07 EP disclosed
US-4202786-A Peroxygen bleaching and compositions therefor FMC CORPORATION (US) 1980-05-13 US disclosed
US-4183913-A CARBODIIMIDE AND HETEROCYCLIC QUATERNARY AMMONIUM COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1980-01-15 US disclosed
US-4113676-A Aqueous dispersions of esters stabilized with carbodiimides PPG INDUSTRIES, INC. (US) 1978-09-12 US disclosed
US-4112065-A Compositions of bis(ortho-substituted phenyl)carbodiimides and quaternary ammonium salts and their use thereof in combatting ectoparasitic tick infestations of animals BAYER AKTIENGESELLSCHAFT (GE) 1978-09-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12065531-B2 Polyglycolic acid resin and production process thereof RPN2, RIOX2, RPN1 GABRA1 1030/4885GABRB2 1504/4885ALDH1A1 3675/4885
US-12559624-B2 Film comprising polylactic acid polymer suitable for graphic articles POT1, PARG, TCP1 GABRA1 1158/4885GABRB2 3099/4885ALDH1A1 373/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.