Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 18/20 | 0.52 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16879493 | 0.87 | GLS (0.50) | GLSBRAF | |
| SCHEMBL16887476 | 0.85 | GLS (0.72) | GLS | |
| SCHEMBL16879484 | 0.83 | GLS (0.50) | GLSBRAF | |
| SCHEMBL16887419 | 0.82 | GLS (0.69) | GLS | |
| SCHEMBL16879585 | 0.78 | GLS (0.83) | GLS | |
| SCHEMBL16879549 | 0.77 | BRAF (0.44) | GLSBRAF | |
| SCHEMBL18135206 | 0.77 | GLS (0.63) | GLS | |
| SCHEMBL16887478 | 0.76 | GLS (0.61) | GLS | |
| SCHEMBL6232367 | 0.76 | CHRM2 (0.50) | — | |
| SCHEMBL21981021 | 0.75 | AOC2 (0.51) | GLSBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015101958-A2 | NOVEL INHIBITORS OF GLUTAMINASE | RHIZEN PHARMACEUTICALS SA (CH) | 2015-07-09 | — | — | WO | disclosed |