Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.88 |
| ▸ | LMNA | P02545 | 1/20 | 0.88 |
| ▸ | TP53 | P04637 | 1/20 | 0.88 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 5/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.45 |
| ▸ | MIF | P14174 | 4/20 | 0.45 |
| ▸ | BACH1 | O14867 | 2/20 | 0.45 |
| ▸ | MAFK | O60675 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 8/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Erysolin SCHEMBL437996 | 0.93 | ALDH1A1 (1.00) | ALDH1A1LMNATP53NAAAKEAP1 | |
| SCHEMBL938891 | 0.91 | ALDH1A1 (0.96) | ALDH1A1LMNATP53NAAAKEAP1 | |
| SCHEMBL21616877 | 0.91 | ALDH1A1 (0.96) | ALDH1A1LMNATP53NAAAKEAP1 | |
| SCHEMBL21616875 | 0.91 | ALDH1A1 (0.96) | ALDH1A1LMNATP53NAAAKEAP1 | |
| SCHEMBL14933788 | 0.91 | ALDH1A1 (0.96) | ALDH1A1LMNATP53NAAAKEAP1 | |
| SCHEMBL25332003 | 0.91 | ALDH1A1 (0.96) | ALDH1A1LMNATP53NAAAKEAP1 | |
| SCHEMBL14797843 | 0.91 | ALDH1A1 (0.96) | ALDH1A1LMNATP53NAAAKEAP1 | |
| SCHEMBL18225463 | 0.86 | — | — | |
| SCHEMBL31350946 | 0.79 | ALDH1A1 (0.57) | ALDH1A1LMNATP53 | |
| SCHEMBL25333023 | 0.78 | ALDH1A1 (0.61) | ALDH1A1LMNATP53NAAAKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820290-B1 | FUNGICIDES TO PREVENT AND CONTROL FUNGAL PATHOGENS | UNIV LAUSANNE (CH) | 2025-07-02 | — | — | EP | claimed |
| US-20250032470-A1 | Electrophilic Androgen Receptor (AR) Antagonists for AR Downregulation and Ferroptosis Induction in Cancer Cells | WAYNE STATE UNIVERSITY (US) | 2025-01-30 | — | — | US | claimed |
| CN-112469279-B | Fungicides for the prevention and control of fungal pathogens | 洛桑大学 | 2022-05-31 | — | — | CN | claimed |
| US-20210106571-A1 | ISOTHIOCYANATE-ANDROGEN RECEPTOR INHIBITOR CONJUGATES FOR APOPTOSIS AND/OR FERROPTOSIS INDUCTION IN CANCER CELLS | WAYNE STATE UNIVERSITY (US) | 2021-04-15 | — | — | US | claimed |
| EP-1313377-B1 | TREATMENT OF HELICOBACTER WITH ISOTHIOCYANATES | FAHEY JED W (US) | 2015-01-21 | — | — | EP | claimed |
| US-20120237566-A1 | INHIBITING STOMACH-ACID RELEASE, REDUCING INFLAMMATION AND PREVENTING AND TREATING CANCER: COMPOSITIONS AND METHODS OF USE | Venture Isles, LLC (US) | 2012-09-20 | — | — | US | claimed |
| US-20120208879-A1 | METHODS AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR TREATING PSORIASIS | GAVISH-GALILEE BIO APPLICATIONS LTD. (IL) | 2012-08-16 | — | — | US | claimed |
| US-20100260737-A1 | COMBINATION BETWEEN AN ISOTHIOCYANATE AND LEVODOPA FOR PARKINSON'S DISEASE TREATMENT | ALMA MATER STUDIORUM - UNIVERSITA' DI BOLOGNA (IT) | 2010-10-14 | — | — | US | claimed |
| EP-2229166-A1 | COMBINATION BETWEEN AN ISOTHIOCYANATE AND LEVODOPA FOR PARKINSON'S DISEASE TREATMENT | Alma Mater Studiorum - Università di Bologna (IT) | 2010-09-22 | — | — | EP | claimed |
| EP-2163238-A2 | Compound for lightening skin tone comprising sulforaphane or sulforaphene or their derivates | Henkel AG & Co. KGaA (DE) | 2010-03-17 | — | — | EP | claimed |
| EP-1841320-A2 | METHODS AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR TREATING PSORIASIS | S.U.L.V.E. Ltd. (IL) | 2007-10-10 | — | — | EP | claimed |
| WO-2006075330-A2 | METHODS AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR TREATING PSORIASIS | S.U.L.V.E. LTD. (IL) | 2006-07-20 | — | — | WO | claimed |
| WO-2006065736-A2 | METHOD OF EXTRACTION OF ISOTHIOCYANATES INTO OIL FROM GLUCOSINOLSATE-CONTAINING PLANTS | JOHNS HOPKINS UNIVERSITY (US) | 2006-06-22 | — | — | WO | claimed |
| US-20060127996-A1 | Method of extraction of isothiocyanates into oil from glucosinolate-containing plants and method of producing products with oil containing isothiocyanates extracted from glucosinolate-containing plants | JOHNS HOPKINS UNIVERSITY | 2006-06-15 | — | — | US | claimed |
| US-20040180843-A1 | Treatment of helicobacter with isothocyanates | BRASSICA FOUNDATION FOR CHEMOPROTECTION RESEARCH, INC. | 2004-09-16 | — | — | US | claimed |
| US-6737441-B2 | PREVENTING OR TREATING PERSISTENT CHRONIC GASTRITIS, ULCERS AND/OR STOMACH CANCER | Fahey, Jed W. | 2004-05-18 | — | — | US | claimed |
| CN-1469711-A | Treatment of helicobacter with isothiocyanates | W | 2004-01-21 | — | — | CN | claimed |
| EP-1313377-A2 | TREATMENT OF HELICOBACTER WITH ISOTHIOCYANATES | Fahey, Jed W. (US) | 2003-05-28 | — | — | EP | claimed |
| US-20020151505-A1 | Treatment of helicobacter with isothiocyanates | FAHEY, JED W. | 2002-10-17 | — | — | US | claimed |
| WO-2002015722-A2 | TREATMENT OF HELICOBACTER WITH ISOTHIOCYANATES | FAHEY JED W (US) | 2002-02-28 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210106571-A1 | ISOTHIOCYANATE-ANDROGEN RECEPTOR INHIBITOR CONJUGATES FOR APOPTOSIS AND/OR FERROPTOSIS INDUCTION IN CANCER CELLS | AR, AIFM2, GSR | ALDH1A1 497/4885LMNA 4879/4885TP53 224/4885 |
| US-20120237566-A1 | INHIBITING STOMACH-ACID RELEASE, REDUCING INFLAMMATION AND PREVENTING AND TREATING CANCER: COMPOSITIONS AND METHODS OF USE | SLC30A5, TRPA1, SLC30A7 | ALDH1A1 1178/4885LMNA 4831/4885TP53 651/4885 |
| US-20250032470-A1 | Electrophilic Androgen Receptor (AR) Antagonists for AR Downregulation and Ferroptosis Induction in Cancer Cells | AR, GSR, GPX1 | ALDH1A1 478/4885LMNA 4870/4885TP53 428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.