Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3627338 | 1.00 | THRB (0.53) | THRBADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL18257694 | 1.00 | THRB (0.53) | THRBADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL12262583 | 1.00 | THRB (0.53) | THRBADRA2AADRA2CLMNAHIF1A | |
| Hydrochloric Acid SCHEMBL22774850 | 0.98 | ALDH1A1 (0.52) | THRBADRA2AADRA2CLMNAHIF1A | |
| Hydrochloric Acid SCHEMBL22774703 | 0.98 | ALDH1A1 (0.52) | THRBADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL9638851 | 0.84 | THRB (0.50) | THRBADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL5474344 | 0.83 | THRB (0.57) | THRBLMNAALDH1A1CYP3A4DPP4 | |
| SCHEMBL3842608 | 0.83 | THRB (0.57) | THRBLMNAALDH1A1CYP3A4DPP4 | |
| SCHEMBL5396533 | 0.83 | THRB (0.57) | THRBLMNAALDH1A1CYP3A4DPP4 | |
| SCHEMBL5474351 | 0.83 | THRB (0.57) | THRBLMNAALDH1A1CYP3A4DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015103505-A2 | DIRECT STEREOSPECIFIC SYNTHESIS OF UNPROTECTED AZIRIDINES FROM OLEFINS | ESS DANIEL HALSELL (US) | 2015-07-09 | — | — | WO | disclosed |