Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3842608 | 1.00 | THRB (0.57) | THRBCYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL5474344 | 1.00 | THRB (0.57) | THRBCYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL5396533 | 1.00 | THRB (0.57) | THRBCYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL14225206 | 0.87 | THRB (0.57) | THRBCYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL12884228 | 0.87 | THRB (0.57) | THRBCYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL15113559 | 0.87 | THRB (0.57) | THRBCYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL9911361 | 0.87 | THRB (0.57) | THRBCYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL680661 | 0.87 | THRB (0.57) | THRBCYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL12894107 | 0.85 | THRB (0.50) | THRBCYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL9638851 | 0.85 | THRB (0.50) | THRBCYP3A4CYP2D6SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317427-B1 | METHOD FOR PRODUCING CHIRAL COMPOUNDS | GRUENENTHAL GMBH (DE) | 2004-12-15 | — | — | EP | claimed |
| CN-1474808-A | Method for producing chipal compounds | — | 2004-02-11 | — | — | CN | claimed |
| US-20030236429-A1 | Process for the production of chiral compounds | GRUENENTHAL GMBH (DE) | 2003-12-25 | — | — | US | claimed |
| CN-117343047-A | Bimetal synergistic promotion system and application thereof in asymmetric synthesis of (R, S) -TBAJ-876 | 上海交通大学 | 2024-01-05 | — | — | CN | disclosed |
| US-20070254906-A1 | Method of Administration of Dopamine Receptor Agonists | DARPHARMA, INC. (US) | 2007-11-01 | — | — | US | disclosed |
| CN-1474808-A | Method for producing chipal compounds | — | 2004-02-11 | — | — | CN | disclosed |
| US-20030236429-A1 | Process for the production of chiral compounds | GRUENENTHAL GMBH (DE) | 2003-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254906-A1 | Method of Administration of Dopamine Receptor Agonists | ADRA1D, DRD2, CHRM3 | THRB 620/4885CYP3A4 590/4885CYP2D6 320/4885 |
| US-20030236429-A1 | Process for the production of chiral compounds | CYP4A11, HSD11B1, CYP4B1 | THRB 4024/4885CYP3A4 5/4885CYP2D6 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.