Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 19/20 | 0.58 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.48 |
| ▸ | ACVR1B | P36896 | 14/20 | 0.46 |
| ▸ | ACVRL1 | P37023 | 11/20 | 0.46 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.46 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18219787 | 0.87 | NUDT1 (0.47) | TGFBR1NUDT1ACVR1BACVRL1ACVR1 | |
| SCHEMBL16888490 | 0.85 | TGFBR1 (0.40) | TGFBR1ACVR1BACVRL1ACVR1BMPR1A | |
| SCHEMBL22270337 | 0.81 | TGFBR1 (0.79) | TGFBR1ACVR1BACVRL1ACVR1BMPR1A | |
| SCHEMBL21620739 | 0.75 | TGFBR1 (0.57) | TGFBR1NUDT1ACVR1BACVRL1ACVR1 | |
| SCHEMBL18219788 | 0.73 | MAPK14 (0.35) | TGFBR1NUDT1ACVR1BACVRL1ACVR1 | |
| SCHEMBL21620589 | 0.73 | TGFBR1 (0.57) | TGFBR1NUDT1ACVR1BACVRL1ACVR1 | |
| SCHEMBL21617838 | 0.73 | TGFBR1 (0.64) | TGFBR1NUDT1ACVR1BACVRL1ACVR1 | |
| SCHEMBL21620670 | 0.73 | TGFBR1 (0.57) | TGFBR1NUDT1ACVR1BACVRL1ACVR1 | |
| SCHEMBL21620605 | 0.73 | TGFBR1 (0.57) | TGFBR1NUDT1ACVR1BACVRL1ACVR1 | |
| SCHEMBL16888489 | 0.72 | TGFBR1 (0.55) | TGFBR1ACVR1BACVRL1ACVR1BMPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015103355-A1 | COMPOUNDS AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. (US) | 2015-07-09 | — | — | WO | disclosed |