SCHEMBL1688856

SCHEMBL1688856

Cc1ccc(Oc2ccc(OCOc3ccc(Oc4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TEAD4 Q15561 1/20 0.56
ALDH1A1 P00352 1/20 0.54
POLB P06746 1/20 0.54
MAPT P10636 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
DRD2 P14416 1/20 0.47
DRD4 P21917 1/20 0.47
DRD3 P35462 1/20 0.47
WDR5 P61964 1/20 0.47
LTA4H P09960 5/20 0.46
ACHE P22303 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
MMP13 P45452 1/20 0.44
HTT P42858 1/20 0.44
KCNH2 Q12809 1/20 0.44
GALR3 O60755 1/20 0.44
KDM4E B2RXH2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1688857 0.92 ACHE (0.52) TEAD4MAPTTDP1DRD2DRD4
Hydrochloric Acid SCHEMBL10552585 0.90 DRD2 (0.50) ALDH1A1POLBMAPTTDP1DRD2
Hydrochloric Acid SCHEMBL10552592 0.90 DRD2 (0.50) ALDH1A1POLBMAPTTDP1DRD2
SCHEMBL19599386 0.85 DRD2 (0.47) ALDH1A1MAPTDRD2DRD4DRD3
SCHEMBL19798030 0.85 DRD2 (0.47) ALDH1A1MAPTDRD2DRD4DRD3
SCHEMBL13839126 0.85 DRD2 (0.47) ALDH1A1MAPTDRD2DRD4DRD3
SCHEMBL19798031 0.85 DRD2 (0.47) ALDH1A1MAPTDRD2DRD4DRD3
SCHEMBL83863 0.84 TEAD4 (0.74) TEAD4ALDH1A1POLBMAPTTDP1
SCHEMBL95343 0.84 TEAD4 (0.74) TEAD4ALDH1A1POLBMAPTTDP1
SCHEMBL83814 0.84 TEAD4 (0.74) TEAD4ALDH1A1POLBMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240019738-A1 DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF JAPAN DISPLAY INC. (JP) 2024-01-18 US disclosed
US-20230133211-A1 PHOTOCHROMIC CYCLIC COMPOUND AND CURABLE COMPOSITION CONTAINING THE PHOTOCHROMIC CYCLIC COMPOUND TOKUYAMA CORPORATION (JP) 2023-05-04 US disclosed
US-9976086-B2 Liquid crystal aligning agent containing polyimide precursor having thermally-leaving group and/or polyimide NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-05-22 US disclosed
US-20160264867-A1 LIQUID CRYSTAL ALIGNING AGENT CONTAINING POLYIMIDE PRECURSOR HAVING THERMALLY-LEAVING GROUP AND/OR POLYIMIDE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-09-15 US disclosed
US-8901353-B2 Polyimide precursor, polyimide, and liquid crystal aligning agent NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-12-02 US disclosed
US-8829153-B2 Polyimide precursor composition containing polyamic acid alkyl ester NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-09-09 US disclosed
US-20120101236-A1 POLYIMIDE PRECURSOR COMPOSITION CONTAINING POLYAMIC ACID ALKYL ESTER NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-04-26 US disclosed
US-20120088888-A1 POLYIMIDE PRECURSOR, POLYIMIDE, AND LIQUID CRYSTAL ALIGNING AGENT NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-04-12 US disclosed
US-20120088888-A1 POLYIMIDE PRECURSOR, POLYIMIDE, AND LIQUID CRYSTAL ALIGNING AGENT NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120088888-A1 POLYIMIDE PRECURSOR, POLYIMIDE, AND LIQUID CRYSTAL ALIGNING AGENT PUF60, F13A1, F12 TEAD4 2913/4885ALDH1A1 4072/4885POLB 1894/4885
US-20230133211-A1 PHOTOCHROMIC CYCLIC COMPOUND AND CURABLE COMPOSITION CONTAINING THE PHOTOCHROMIC CYCLIC COMPOUND CRY1, CCNL2, CCNT1 TEAD4 1643/4885ALDH1A1 2749/4885POLB 484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.