Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1688916 | 0.90 | LMNA (0.44) | ALDH1A1MAPTKDM4EHSP90AA1RAB9A | |
| SCHEMBL1688932 | 0.88 | MAPT (0.40) | ALDH1A1MAPTKDM4EADORA2AHSP90AA1 | |
| SCHEMBL5611833 | 0.87 | MAPT (0.41) | ALDH1A1MAPTADORA2AHSP90AA1RAB9A | |
| SCHEMBL5611446 | 0.87 | MAPT (0.43) | ALDH1A1MAPTHSP90AA1MEN1KMT2A | |
| SCHEMBL5611687 | 0.85 | MAPT (0.52) | PKMALDH1A1MAPTKDM4EHSP90AA1 | |
| SCHEMBL1689243 | 0.85 | MAPT (0.51) | ALDH1A1MAPTKDM4EADORA2AHSP90AA1 | |
| SCHEMBL1689427 | 0.84 | MAPT (0.44) | ALDH1A1MAPTHSP90AA1RAB9AMEN1 | |
| SCHEMBL1689138 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPTHSP90AA1RAB9AAURKA | |
| SCHEMBL1689325 | 0.83 | MAPT (0.41) | ALDH1A1MAPTHSP90AA1MEN1KMT2A | |
| SCHEMBL1689071 | 0.83 | AOC3 (0.45) | ALDH1A1MAPTKDM4EADORA2AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807429-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM, LLC (BM) | 2007-07-18 | — | — | EP | claimed |
| WO-2006047516-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2006-05-04 | — | — | WO | claimed |