SCHEMBL16889604

SCHEMBL16889604

c1cc2c3c(c1)Oc1c(ccc4ccccc14)B3c1cc3c(cc1O2)oc1ccccc13

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.35
ALDH1A1 P00352 8/20 0.35
MAPT P10636 6/20 0.35
HPGD P15428 5/20 0.35
KMT2A Q03164 4/20 0.35
MEN1 O00255 3/20 0.35
AHR P35869 2/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
GLA P06280 2/20 0.33
TSHR P16473 1/20 0.33
HTT P42858 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
DUSP3 P51452 1/20 0.33
MAOA P21397 1/20 0.33
HNF4A P41235 1/20 0.33
GAA P10253 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16889481 0.88 MAPT (0.44) KDM4EALDH1A1MAPTHPGDKMT2A
SCHEMBL16889588 0.87 HNF4A (0.37) KDM4EALDH1A1MAPTHPGDKMT2A
SCHEMBL16889665 0.84 MAPT (0.41) KDM4EALDH1A1MAPTHPGDKMT2A
SCHEMBL16890662 0.84 MAPT (0.41) KDM4EALDH1A1MAPTHPGDKMT2A
SCHEMBL22785513 0.82
SCHEMBL16889492 0.82 MAPT (0.44) KDM4EALDH1A1MAPTHPGDKMT2A
SCHEMBL16889223 0.82 ALDH1A1 (0.37) KDM4EALDH1A1MAPTHPGDAHR
SCHEMBL16889703 0.82 MAPT (0.37) KDM4EALDH1A1MAPTHPGDKMT2A
SCHEMBL16889515 0.80 ALDH1A1 (0.32) KDM4EALDH1A1AHRTSHRHSD17B10
SCHEMBL16890056 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3345911-A1 POLYCYCLIC AROMATIC COMPOUNDS AND THEIR USE AS ORGANIC DEVICE MATERIAL Kwansei Gakuin Educational Foundation (JP) 2018-07-11 EP disclosed
WO-2015102118-A1 POLYCYCLIC AROMATIC COMPOUND 学校法人関西学院 2015-07-09 WO disclosed